Sökning: "NGAL"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet NGAL.

  1. 1. Experimental septic shock – Effects of endotoxemia with special reference to pathophysiological responses in the pig

    Författare :Ewa Söderberg; Miklós Lipcsey; Mats B Eriksson; Anders Larsson; Jan Sjölin; Sten Lindahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endotoxin; inflammatory response; animal model; timing; steroid treatment; NGAL; Calprotectin; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Sepsis and septic shock are conditions, with severe outcome or in many cases death. Sepsis is a systemic inflammatory response trigger by bacteraemia but systemic inflammatory response can also be triggered by major trauma, major surgery, pancreatitis, severe burns etc. LÄS MER

  3. 2. Secretory Leukocyte Protease Inhibitor (SLPI) in the gastrointestinal tract in man

    Författare :Max Nyström; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; elastase inhibitors; human leukocyt proteases; Plasma protease inhibitors; NGAL; Ulcerative colitis; Antileukoprotease; IBD; traumatologi; ortopedi; traumatology; orthopaedics; Immunology; serology; transplantation; Immunologi; serologi; Kirurgi;

    Sammanfattning : Secretory leukocyte protease inhibitor is a 11.7 kDa acid stable serine protease inhibitor. SLPI has been shown to be the dominant protease inhibitor in bronchial secretions and has been used in treatment of pulmonary emphysema. LÄS MER

  4. 3. Infammatory response to hyperbaric trauma. An experimental and clinical study

    Författare :Anders Ersson; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesiology; intensive care; Anestesiologi; intensivvård; Complement; Cytokines; NGAL; Secretory leukocyte protease inhibitor; decompression sickness; inflammation; Diving; bubbles;

    Sammanfattning : Reductions in ambient pressure liberates gas in various tissues and can result in decompression illness. In this thesis the patophysiological implications of a blood gas interface resulting from decompression was investigated with reference to the influence on biochemical mediators of inflammation. LÄS MER

  5. 4. Cellular and molecular mechanisms in abdominal aortic aneurysm growth and rapture

    Författare :Monsur Kazi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AAA; thrombus; proteases; NGAL; mast cells;

    Sammanfattning : Fragmentation of elastin, loss of smooth muscle cells (SMCs) and accumulation of inflammatory cells are the histological landmarks of abdominal aortic aneurysm (AAA). In larger aneurysms, an intraluminal thrombus is almost always present. It has been suggested that the thrombus predisposes for AAA rupture. LÄS MER

  7. 5. The nuclear factor k[kappa]B signal transduction pathway : its role in atherogenesis and intimal hyperplasia

    Författare :De-xiu Bu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; intimal hyperplasia; NF-kappaB; NGAL; Telomerase; Leukotriene B4;

    Sammanfattning : Vascular inflammation is a hallmark of major cardiovascular diseases such as atherosclerosis, and also suggested as a critical component implicated in intimal hyperplasia. Given its central role in regulating expression of inflammatory genes, the nuclear factor kappaB (NF-kappaB) signal transduction pathway was postulated to play an important role in these pathological processes. LÄS MER