Sökning: "Clas Une"

Hittade 1 avhandling innehållade orden Clas Une.

  1. 1. Studies of the recognition and activation of natural killer cells

    Författare :Clas Une; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NK cells; activation; cytotoxicity; IFN-[gamma] IFN-[alpha] [beta]; IL-12; G-PI; MHC class I;

    Sammanfattning : Natural killer (NK) cells mediate part of the innate immune response that impedes the spread of invading microorganisms and shapes the downstream adaptive immune response. NK cells spontaneously kill tumor cells and other cells upon contact. Killing requires engagement of germline encoded receptors that mediate positive and negative signals. LÄS MER