Sökning: "Antiretroviral therapy"

Visar resultat 21 - 25 av 107 avhandlingar innehållade orden Antiretroviral therapy.

  1. 21. Antiretroviral drug resistant HIV-1 in women and children living in Honduras

    Författare :Leda Parham; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antiretroviral therapy (ART) in HIV infected pregnant women contributes to the prevention of HIV transmission to the newborn. However, as ART can also induce HIV drug resistance during suboptimal levels of virological suppression a major concern is the subsequent risk for transmitted drug resistant (TDR) virus to the child. LÄS MER

  3. 22. Characterization of HIV-1 in the central nervous system during suppressive therapy

    Författare :Viktor Dahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Combination antiretroviral therapy (cART) is effective in suppressing HIV-1 RNA levels below the lower-limit of detection of clinical assays (.... LÄS MER

  4. 23. The HIV-1 epidemic in Ethiopia – transmission patterns, antiretroviral drug resistance and treatment outcomes

    Författare :Dawit Assefa; Malmö Klinisk virologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HIV-1; HIV drug resistance HIVDR ; Phylodynamics; Phylogenetic; Molecular epidemology; transmitted HIVDR; acquired HIVDR; pre-treatment HIVDR; Integrase strand transfer inhibitors INSTI ; Ethiopia; antiretroviral therapy;

    Sammanfattning : A comprehensive understanding of local HIV epidemiology is essential for monitoring transmission, designing, implementing, and evaluating HIV intervention strategies. In paper I, we used a total of 1276 HIV-1 subtype C pol sequences and employed state-of-art phylogenetic and phylodynamic tools to describe the molecular epidemiology of HIV in Ethiopia. LÄS MER

  5. 24. Optimization of pediatrics antiretroviral treatment outcomes among HIV infected children in Ethiopia

    Författare :Birkneh Tilahun Tadesse; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Ending the HIV/AIDS epidemic by 2030 is a global agenda. To meet this global goal, having safe and effective antiretroviral therapy is a key requirement. In Ethiopia, the safety and efficacy of combination antiretroviral therapy in HIV infected pediatric population is poorly studied. LÄS MER

  7. 25. Characterization of HIV-1 RNA and DNA during long-term suppressive therapy

    Författare :Susanne von Stockenström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human immunodeficiency virus (HIV) is the virus causing acquired immune deficiency syndrome (AIDS). Since the discovery of HIV/AIDS over three decades ago, this disease has claimed millions of lives. One of the major accomplishments of modern history came in 1996, when combination antiretroviral therapy (cART) was introduced. LÄS MER