Sökning: "Anergy"

Visar resultat 16 - 20 av 20 avhandlingar innehållade ordet Anergy.

1. 16. Cellular immune responses in allogeneic and xenogeneic transplantation models

   Författare :Annacarin Wallgren; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : The introduction of immunosuppressive agents and improvements in surgical techniques and ancillary care has made allotransplantation a routine procedure. However, improvements in short-term graft survival rates have not been accompanied by a similar improvement in long-term outcome due to the process of therapy-resistant chronic allograft rejection. LÄS MER

3. 17. Genetic polymorphism and natural killer cell activity in multiple myeloma

   Författare :Chengyun Zheng; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Multiple Myeloma (MM) is a B cell malignancy characterised by an accumulation of clonal neoplastic plasma cells in bone marrow. Its aetiology remains unknown. Remarkable racial differences in the incidence of MM and occurrence of familial MM suggest that genetic factors may play a role in the development of MM. LÄS MER

4. 18. Modulation of experimental T cell autoimmunity in the nervous system with emphasis on nasal tolerance

   Författare :Xue-Feng Bai; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Experimental autoimmune neuritis (EAN) and encephalomyelitis (EAE) are animal models of Guillian-Barre syndrome (GBS) and multiple sclerosis (MS), representing human demyelinating diseases of the peripheral nervous system (PNS) and central nervous system (CNS), respectively. CD4+ T cells recognizing myelin antigens and producing cytokines play central roles in the pathogenesis of both EAN and EAE and perhaps of GBS and MS. LÄS MER

5. 19. Novel treatment strategies and regulation of IgE-mediated allergic disease

   Författare :Sarah Thunberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Allergic symptoms such as rhinoconjunctivitis, asthma or gastrointestinal symptoms, triggered by inhaled or ingested allergens cross-linking allergen-specific IgE on mast cells or basophils, are defined as IgE-mediated allergy. The major allergens from birch pollen (Bet v 1) and cat dander (Fel d 1) are two common allergens eliciting allergic disease. LÄS MER

7. 20. Intercellular protein transfer and regulation of inhibitory NK receptor accessibility

   Författare :Katja Andersson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : NK cells are important players of innate immunity and capable of promoting specific responses of the adaptive immune system. NK cells possess the ability to recognise and eliminate virus-infected cells, tumour cells and allogeneic bone marrow grafts. LÄS MER