Sökning: "virulence plasmid"

Visar resultat 16 - 20 av 20 avhandlingar innehållade orden virulence plasmid.

  1. 16. Antibiotic Resistance and Fitness of Escherichia coli in the Infantile Commensal Microbiota

    Författare :Nahid Karami; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ampicillin; tetracycline; in vivo fitness; persistence; gene transfer; intestinal; blaTEM Escherichia coli;

    Sammanfattning : Microbial resistance to antibiotics is a growing problem worldwide. Resistance develops not only in microbes which are the targets of the antibiotic treatment, but also in those belonging to the normal microbiota of the treated host. Little is known on the ecological consequences of antibiotic resistance in commensal bacteria. LÄS MER

  3. 17. Genetic vaccination against acute viral disease

    Författare :Marina N Fleeton; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Semliki Forest virus; Alphavirus. Influenza A virus; DNA vaccines. Influenza vaccine. Respiratory Syncytial Viruses; Louping Ill. Flavivirus Infections;

    Sammanfattning : This thesis describes the development of recombinant vaccines based on the Semliki Forest virus (SFV) expression system. Immunisation of mice with recombinant virus particles, a layered DNA/RNA plasmid vector, and recombinant self-replicating RNA were carried out and the protective effect of these recombinant vaccines against viral challenge were examined. LÄS MER

  4. 18. Mechanisms of adaptive mutations in bacteria

    Författare :Elisabeth Kugelberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bacteria have the ability to adapt to various challenging environments. The rate, extent and consequences of bacterial adaptation depend on both microbial and environmental factors. LÄS MER

  5. 19. Enterohemorrhagic Escherichia coli, EHEC.Microbiological diagnosis, characterisation and clinical bacteriological aspects

    Författare :Christina Welinder-Olsson; Göteborgs universitet; []
    Nyckelord :Escherichia coli; EHEC; VTEC; verocytotoxin; PFGE; EHEC-hemolysin; aerobactin; diarrhoea; HUS;

    Sammanfattning : Enterohemorrhagic Escherichia coli (EHEC) constitutes a group of E. coli that in the past two decades has been the cause of several outbreaks of gastrointestinal disease. The microorganism causes hemorrhagic colitis (HC) and haemolytic uremic syndrome (HUS) in 5-10% of the patients, 30% of the HUS patients develop remaining kidney injuries. LÄS MER

  7. 20. Regulation of the multi-functional protein YscU in assembly of the Yersinia type III secretion injectisome

    Författare :Ho Ngoc Hoang Oanh; Magnus Wolf-Watz; Anna Linusson Jonsson; Maria Sunnerhagen; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Type III secretion system T3SS ; injectisome; Yersinia pseudotuberculosis; inhibitors; Yops; YscU; YscP; YscI; disorder-to-order transition; nuclear magnetic resonance NMR ; circular dichroism CD ; isothermal titration calorimetry ITC ; biologisk kemi; biological chemistry;

    Sammanfattning : Yersinia pseudotuberculosis is a Gram-negative zoonotic pathogenic bacterium causing gastroenteritis in human and animals. It shares a conserved virulence plasmid encoding for a needle-like secretion machinery, or type III secretion system, which can be found in other pathogenic Gram-negative bacteria. LÄS MER