Sökning: "utveckling av läkemedel"

Visar resultat 1 - 5 av 120 avhandlingar innehållade orden utveckling av läkemedel.

  1. 1. Selective serotonin re-uptake inhibitors in the environment : Effects of citalopram on fish behaviour

    Författare :Martin Kellner; Håkan Olsén; Inger Porsch-Hällström; Magnus Breitholtz; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Citalopram; SSRI; stickleback; Baltic; behaviour; fish; feeding; anxiety; boldness; serotonin; development; Storspigg; serotonin; östersjön; SSRI; läkemedel; miljö; citalopram; ätbeteende; beteende; utveckling; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Selective serotonin re-uptake inhibitors (SSRIs) are a class of anxiolytic and anti-depressant drugs. SSRIs act on the evolutionarily ancient serotonergic system which is virtually identical throughout the vertebrate phylum. LÄS MER

  3. 2. Design strategies for new drugs targeting multicomponent systems : focusing on class II MHC proteins and acetylcholinesterase

    Författare :Cecilia Lindgren; Anna Linusson; Antti Poso; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acetylcholinesterase; class II MHC protein; drug design; molecular dynamics simulation; multicomponent system; nerve agent; oxime; quantitative structure-activity relationship; reactivator; rheumatoid arthritis; statistical molecular design; T-cell receptor;

    Sammanfattning : The field of medicinal chemistry is constantly evolving. Aided by advances within techniques as well as knowledge of biological systems, increasingly complex targets and drugs can be considered. LÄS MER

  4. 3. Change in the Pharmaceutical Industry : Aspects on Innovation, Entrepreneurship, Openness, and Decision Making

    Författare :Thomas Hedner; Magnus Klofsten; Johan Braet; Mirjam Knockaert; Linköpings universitet; []
    Nyckelord :Pharmaceutical industry; Big Pharma; life sciences; drug discovery; drug development; R D; business model; innovation; closed innovation; open innovation; entrepreneurship; intellectual property; multiple stakeholders; decision making; judgment; uncertainty; go no-go; go no-go recycle; company; SME.; Läkemedelsindustri; Big Pharma; biovetenskap; läkemedelsutveckling; utveckling av läkemedel; FoU; affärsmodell; innovation; stängd innovation; öppen innovation; entreprenörskap; immaterialrätt; beslutsfattande; osäkerhet; go no-go; go no-go recycle; företag; små och medelstora företag;

    Sammanfattning : Over the past century, the pharmaceutical industry has been a major contributor of individual and population health and societal wealth. Its products and services have contributed to longevity of large groups of patients and symptom relief from major diseases. LÄS MER

  5. 4. Development and applications of NMR relaxation methods to study protein and ligand dynamics

    Författare :Sven Wernersson; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear magnetic resonance; NMR; NMR relaxation; Method development; Protein dynamics; BRD4; Galectin 3; Kärnmagnetisk resonansspektroskopi; proteindynamik; Metodutveckling; NMR; BRD4; Galektin 3;

    Sammanfattning : This thesis involves the study of proteins. These molecules exist in many variants, and perform most of our bodily functions. This includes signaling (for example the presence of capsaicin, which makes food spicy), molecular transport (including oxygen), catalysis (including food digestion) and part of our body structure (such as muscles). LÄS MER

  7. 5. Managing chemotherapy risks : Learning from medication errors and developing a national knowledge source for chemotherapy regimens

    Författare :Ann-Sofie Fyhr; Ergonomi och aerosolteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Chemotherapy; Chemotherapy regimens; Medication errors; Patient safety; e-library; Standardisation; User evaluation; Usability; Chemotherapy; Chemotherapy regimens; Medication errors; Patient safety; e-library; Standardisation; User evaluation; Usability;

    Sammanfattning : The basics in cancer treatment are surgery, radiation therapy, and treatment with cancer drugs, often combined. Chemotherapy regimens that define the drugs used, the dosage, the frequency and duration of drug administration, have been developed and used for different cancer diagnoses. LÄS MER