Sökning: "tumour cell proliferation"
Visar resultat 1 - 5 av 128 avhandlingar innehållade orden tumour cell proliferation.
1. Cyclin E overexpression and associated events in human breast cancer
Sammanfattning : Unrestrained proliferation is a hallmark of cancer and genetic defects within G1/S-phase regulation and the pRb pathway occur frequently. Proliferation control can be circumvented either by excess cyclin D1 or cyclin E, alterations that can define two alternative tumour biologic pathways in breast cancer. LÄS MER
2. Proliferation, Invasion and p16 Localisation in Malignancies
Sammanfattning : Uncontrolled proliferation and invasion are two characteristics in tumour development and progression. Previous studies have shown that invading tumour cells in colorectal cancer have low proliferation in parallel to upregulation of the tumour suppressor p16. LÄS MER
3. Genetic and Epigenetic Profiling of Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia
Sammanfattning : Mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL) both belong to the group of mature B-cell malignancies. However, MCL is typically clinically aggressive while the clinical course of CLL varies. LÄS MER
4. CD93 in regulation of vascular function and tumour progression
Sammanfattning : To achieve successful vascular targeting in cancer, a better understanding of the molecular mechanisms that lead to tumour vascular abnormalities is required. The transmembrane protein CD93 is highly expressed in the vasculature of several tumours including glioblastoma and has emerged as a potential anti-angiogenic target. LÄS MER
5. Cancer and Therapy: A look into stemness and the tumour microenvironment
Sammanfattning : Therapy is the often-used treatment for cancer patients, even those that undergo resection surgery. While milestones have been surpassed throughout the decades for a number of cancer types, there are those that comprise of characteristics limiting effectiveness of treatments. LÄS MER
