Sökning: "treatment cascade"
Visar resultat 1 - 5 av 111 avhandlingar innehållade orden treatment cascade.
1. Targeted therapeutic strategies for prostate cancer treatment using novel lipid kinase inhibitors in combination with current drugs
Sammanfattning : Prostate cancer (PCa) is one of the most common cancer types and the fifth cancer-related cause of death among Western world men. The sex steroid hormone, androgen and androgen receptor (AR) play important roles in PCa progression. LÄS MER
2. The Burden of Epilepsy : using population-based data to define the burden and model a cost-effective intervention for the treatment of epilepsy in rural South Africa
Sammanfattning : Rationale Epilepsy is a common, chronic, neurological condition that disproportionately affects individuals living in low- and middle- income countries, including much of sub-Saharan Africa. Epilepsy is treatable, with the majority of individuals who take anti-epileptic drugs experiencing a reduction, or elimination, of seizures. LÄS MER
3. Effects of Flow Structure on Particle Separation in Dissolved Air Flotation
Sammanfattning : Dissolved Air Flotation (DAF) is a separation process in water and wastewater treatment. The removal function is based on reducing the density of the particle by producing aggregates of the particles and added micro-bubbles of air, thus lifting the aggregates to the water surface, where they can be removed as sludge. LÄS MER
4. Alzheimer disease : subcellular Aβ mechanisms and treatment strategies
Sammanfattning : The amyloid β-peptide (Aβ) is the key molecule in the pathogenesis of Alzheimer disease (AD), but the mechanisms of its toxicity are still largely unknown. This thesis includes studies aimed at studying Aβ induced mechanisms in neurons at the subcellular level and explore effective AD treatment strategies. LÄS MER
5. Persistent inflammatory pathways in rheumatoid arthritis despite anti-rheumatic treatment
Sammanfattning : The past years have witnessed tremendous progress in the treatment of rheumatoid arthritis, a chronic debilitating autoimmune disease mainly characterized by joint inflammation with progressive tissue destruction and loss of function. This condition affects 0. LÄS MER