Sökning: "njure"

Visar resultat 16 - 20 av 26 avhandlingar innehållade ordet njure.

  1. 16. Prospective and longitudinal human studies of lead and cadmium exposure and the kidney

    Författare :Johan Nilsson Sommar; Ingvar A Bergdahl; Max Petzold; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cadmium; end-stage renal disease; kidney; lead; longitudinal; matched case-control; mixed effects; prospective; Occupational and Environmental Medicine; arbets- och miljömedicin;

    Sammanfattning : Cadmium and lead accumulate in humans and can have toxic effects. Exposure to cadmium is well known to cause kidney damage. Cadmium binds to metallothioneins, proteins that play a role in cadmium transport. LÄS MER

  2. 17. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Författare :Lotta Gustafsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; proteasome stress; HAMLET; human milk; tumor-cell death; clinical trial; rat xenograft model; skin papilloma; glioblastoma;

    Sammanfattning : HAMLET (human alpha-lactalbumin made lethal to tumor cells), a molecular complex derived from human milk, is an interesting new tool in cancer research since it induces programmed cell death in tumor cells while leaving normal, differentiated cells unharmed. The in vivo effects of HAMLET were studied in a rat xenograft model of human glioblastoma. LÄS MER

  3. 18. Register studies of cancer in the Southern Health Care Region in Sweden

    Författare :Bo Attner; Medicinsk onkologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer risk; epidemiology; incidence; comorbidity; survival; partner; health care costs; population-based register study;

    Sammanfattning : The overall aim was to study different aspect of health care use and health care costs on a population based level for persons with cancer and their partners, and from an individual level to explore the impact of comorbidities in incidence and survival. In the beginning of the study all persons in the Southern Health Care Region in Sweden diagnosed with colon, rectal, breast, prostate and lung cancer during the period 2000 to 2005 were identified via the Swedish Cancer Register. LÄS MER

  4. 19. Structure and expression of the TP and EP1 prostanoid receptor genes

    Författare :Björn Båtshake; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuropsykologi; Neurologi; neurofysiologi; Neurology; neuropsychology; neurophysiology;

    Sammanfattning : Prostanoids are ubiquitously distributed lipid signaling molecules derived from arachidonic acid, that exhibit numerous and diverse biological effects in a variety of physiological and pathophysiological conditions. The cell surface receptors for the prostanoids belong to the family of G protein-coupled receptors. LÄS MER

  5. 20. Bioengineering and Cell-derived Strategies for Salivary Gland Regeneration

    Författare :Jiao DONG; Lungbioengineering och regeneration; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular vesicles; precision-cut tissue slices; histology scoring; sustainable histology; salivary gland; human dental pulp stem cells; extracellulära vesiklar; stamceller från mänsklig tandmassa; precisionsskurna vävnadsskivor; Spottkörtel; hållbar histologi och histologipoäng;

    Sammanfattning : Xerostomia (dry mouth symptoms) is a group of incurable debilitating conditions of salivary glands caused by aging, radiation/chemical exposure, or aberrant inflammation in the salivary glands. During this PhD thesis, we aimed to evaluate whether cell-derived strategies (e.g. LÄS MER