Sökning: "mixed effects"

Visar resultat 1 - 5 av 754 avhandlingar innehållade orden mixed effects.

  1. 1. Contributions to nonlinear mixed-effects modeling

    Författare :Jacob Leander; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; nonlinear mixed-effects models; stochastic differential equations; parameter estimation; extended Kalman filter; sensitivity equations; stochastic differential equations;

    Sammanfattning : The topic of this thesis is nonlinear mixed-effects models. A nonlinear mixed-effects model is a hierarchical regression model used to analyze measurements from several individuals simultaneously, which allows sharing of information between similar individuals. LÄS MER

  3. 2. Bättre framtidsutsikter? Blandade bostadsområden och grannskapseffekter : En analys av visioner och effekter av blandat boende

    Författare :Zara Bergsten; Lena Magnusson Turner; Kerstin Westin; Uppsala universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Social mix policy; neighbourhood effects; socioeconomic career; social integration; urban planning; multilevel modelling; Human geography; economic geography; Kulturgeografi; ekonomisk geografi; Geography; Geografi;

    Sammanfattning : Internationally, the effect of social composition in urban neighbourhoods on individuals’ life opportunities has been given increased attention both by researchers and policymakers. Socially mixed neighbourhoods have been seen by policymakers as a measure to create better prerequisites for social upward movement and increased social integration. LÄS MER

  4. 3. Nonlinear Mixed Effects Modeling of Combination Therapies in Oncology

    Författare :Marcus Baaz; Stiftelsen Fraunhofer-Chalmers Centrum för Industrimatematik (FCC); []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacol- ogy; Radiation Therapy; Oncology; Mathematical Modeling; Combination Therapy; Nonlinear Mixed Effects;

    Sammanfattning : It has been shown that simultaneous administration of two or more anticancer agents can have a beneficial effect on cancer patients. This type of treatment is called combination therapy and is nowadays commonly used in the fight against cancer. LÄS MER

  5. 4. Mixed Effects Modeling of Deterministic and Stochastic Dynamical Systems - Methods and Applications in Drug Development

    Författare :Jacob Leander; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; pharmacometrics; pharmacokinetics; mixed effects; drug development; pharmacodynamics; parameter estimation; time-to-event; mathematical modeling; dynamical systems;

    Sammanfattning : Mathematical models based on ordinary differential equations (ODEs) are commonly used for describing the evolution of a system over time. In drug development, pharmacokinetic (PK) and pharmacodynamic (PD) models are used to characterize the exposure and effect of drugs. LÄS MER

  7. 5. Ontogenetic bottlenecks : effects on intraguild predation systems and ecosystem efficiency

    Författare :Birte Reichstein; Lennart Persson; André M. De Roos; Priyanga Amarasekare; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mixed interactions; cannibalism; life-history omnivory; ontogenetic niche shift; biomass overcompensation; biomass production; ontogenetic asymmetry; indirect effects; biology; biologi; zooekologi; Animal Ecology;

    Sammanfattning : Size-dependent differences between individuals in size-structured organisms have fundamental effect on population and community dynamics. Intraguild predation (IGP) is one specifically interesting constellation that often arises when two size-structured populations interact. LÄS MER