Sökning: "mass cytometry"

Visar resultat 1 - 5 av 34 avhandlingar innehållade orden mass cytometry.

  1. 1. Methods and models for 2D and 3D image analysis in microscopy, in particular for the study of muscle cells

    Författare :Patrick Karlsson Edlund; Ewert Bengtsson; Joakim Lindblad; Carolina Wählby; Fritz Albregtsen; Uppsala universitet; []
    Nyckelord :medical image analysis; image segmentation; fluorescence microscopy; cytometry; human skeletal muscle;

    Sammanfattning : Many research questions in biological research lead to numerous microscope images that need to be evaluated. Here digital image cytometry, i.e., quantitative, automated or semi-automated analysis of the images is an important rapidly growing discipline. LÄS MER

  3. 2. Peripheral immunity in patients with autoimmune endocrine diseases and the influence of physiological adaptions during pregnancy

    Författare :Louise Magnusson; Per-Ola Carlsson; Rosaura Casas; Ola Winqvist; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; Hashimoto´s thyroiditis; Graves´ disease; autoimmune Addison´s disease; antigen-presenting cells; B cells; non-classical monocytes; NK cells; memory CD8 T cells; CDCP1; SLAMF1; inflammation; lymphocyte activation; pregnancy; β-cell function; C-peptide; plasma proteome; prolactin; prokineticin-1; glucagon; oral glucose tolerance test; mass cytometry; proximity extension assay; Medicinsk vetenskap; Medical Science; Klinisk immunologi; Clinical Immunology; Endocrinology and Diabetology; Endokrinologi och Diabetologi; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : Type 1 diabetes (T1D), Hashimoto’s thyroiditis (HT), Graves’ disease (GD), and autoimmune Addison’s disease (AD) appear to share immunogenetic mechanisms. This idea is not novel, as “autoimmune tautology” is an established concept. LÄS MER

  4. 3. PROBING SECRETORY VESICLES AND LIPOSOME MODEL SYSTEMS USING NANOSCALE ELECTROCHEMISTRY AND MASS SPECTROMETRY

    Författare :Jelena Lovric; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neuroendocrine cells; NanoSIMS; liposomes; neurotransmitters; large dense core vesicles; Exocytosis; ToF-SIMS; vesicle electrochemical cytometry; electrochemistry; amperometry;

    Sammanfattning : Cellular communication is based on the process of exocytosis, regulated release of chemical messengers into the extracellular space. These messengers, neurotransmitters, are packed into vesicles that during exocytosis fuse with the plasma membrane and release their content. LÄS MER

  5. 4. Mesenchymal heterogeneity in the adult human lung

    Författare :Måns Kadefors; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lung; Extracellular matrix; Adventitia; Fibroblast; mesenchymal cell; Alveolar epithelial cell; Fibrosis; Idiopathic pulmonary fibrosis; Mass spectrometry; RNA-sequencing;

    Sammanfattning : The human lung is a complex tissue consisting of a heterogeneous mix of different structures and cells, each which a specific role that together contribute to the primary function of the organ: the gas exchange. Different mesenchymal cells populate the interstitial areas around airways and blood vessels and form the connective tissue together with the extracellular matrix. LÄS MER

  7. 5. Jejunoileal bypass for morbid obesity : studies of the long-term effects

    Författare :Anders Sylvan; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Jejunoileal bypass; Obesity; Surgery; Liver biopsy; Fibrinolytic system; Colonoscopy; Flow cytometry; Cancer risk;

    Sammanfattning : This study was aimed at investigating adverse and beneficial long-term effects of jejunoileal bypass (JIB) sugery in obese patients. The JIB was the first widly used surgical procedure for treatment of morbid obesity. The weight loss was remarkable, but the procedure was declared not appropiate for obesity surgery in the late 1970's. LÄS MER