Sökning: "RNA-sequencing"

Visar resultat 1 - 5 av 79 avhandlingar innehållade ordet RNA-sequencing.

  1. 1. Progression of RNA-sequencing to single-cell applications

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Daniel Ramsköld; Karolinska Institutet.; Karolinska Institutet.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : New methods enable new discoveries. My time as a PhD student has run in parallel with the maturation of the RNA-seq method, and I have used it to discover basic properties of gene expression and transcriptomes. My part has been bioinformatics – the computer analysis of biological data. LÄS MER

  2. 2. Analysis of RNA and DNA sequencing data Improved bioinformatics applications

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Benjamín Sigurgeirsson; KTH.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Biotechnology; Bioteknologi;

    Sammanfattning : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. LÄS MER

  3. 3. Transcriptome-wide analysis in cells and tissues

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Sanja Vickovic; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA-sequencing; single cells; spatially resolved transcriptomics; 3D profiling.; Biotechnology; Bioteknologi;

    Sammanfattning : High-throughput sequencing has greatly influenced the amount of data produced and biological questions asked and answered. Sequencing approaches have also enabled rapid development of related technological fields such as single-cell and spatially resolved expression profiling. LÄS MER

  4. 4. Spatially resolved and single cell transcriptomics

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Fredrik Salmén; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spatial; transcriptomics; single cell; 3D; RNA-sequencing; Biotechnology; Bioteknologi;

    Sammanfattning : In recent years, massive parallel sequencing has revolutionized the field of biology and has provided us with a vast number of new discoveries in fields such as neurology, developmental biology and cancer research. A significant area is deciphering gene expression patterns, as well as other aspects of transcriptome information, such as the impact of splice variants and mutations on biological functions and disease development. LÄS MER

  5. 5. Genome-wide Characterization of RNA Expression and Processing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ammar Zaghlool; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. LÄS MER