Sökning: "RNA-sequencing"

Visar resultat 1 - 5 av 39 avhandlingar innehållade ordet RNA-sequencing.

  1. 1. Analysis of RNA and DNA sequencing data Improved bioinformatics applications

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Benjamín Sigurgeirsson; KTH.; [2016]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Biotechnology; Bioteknologi;

    Sammanfattning : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. LÄS MER

  2. 2. Transcriptome-wide analysis in cells and tissues

    Detta är en avhandling från Stockholm : KTH Royal Institute of Technology

    Författare :Sanja Vickovic; KTH.; [2017]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA-sequencing; single cells; spatially resolved transcriptomics; 3D profiling.; Biotechnology; Bioteknologi;

    Sammanfattning : High-throughput sequencing has greatly influenced the amount of data produced and biological questions asked and answered. Sequencing approaches have also enabled rapid development of related technological fields such as single-cell and spatially resolved expression profiling. LÄS MER

  3. 3. Genome-wide Characterization of RNA Expression and Processing

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ammar Zaghlool; Uppsala universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA sequencing; RNA splicing; RNA processing; Gene expression; Molekylär genetik; Molecular Genetics;

    Sammanfattning : The production of fully mature protein-coding transcripts is an intricate process that involves numerous regulation steps. The complexity of these steps provides the means for multilayered control of gene expression. LÄS MER

  4. 4. Multifaceted RNA-mediated regulatory mechanisms in Streptococcus pyogenes

    Detta är en avhandling från Umeå : Umeå university

    Författare :Anaïs Le Rhun; Umeå universitet.; Umeå universitet.; Umeå universitet.; [2015]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Streptococcus pyogenes; small RNAs; CRISPR; Cas9; tracrRNA; RNases; gene expression; RNA sequencing; Infectious Diseases; infektionssjukdomar; mikrobiologi; Microbiology;

    Sammanfattning : Bacterial pathogens rely on precise regulation of gene expression to coordinate host infection processes and resist invasion by mobile genetic elements. An interconnected network of protein and RNA regulators dynamically controls the expression of virulence factors using a variety of mechanisms. LÄS MER

  5. 5. Metabolic Engineering of Central Carbon Metabolism in Saccharomyces cerevisiae The contribution of systems biology to physiological studies

    Detta är en avhandling från Chalmers University of Technology

    Författare :Marta Papini; Chalmers tekniska högskola.; Chalmers University of Technology.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Övrig biologi; Other biology; Funktionsgenomik; Functional genomics; Metabolic engineering; system biology; Saccharomyces cerevisiae; DNA microarrays; RNA-sequencing; 13Cbased flux analysis; fermentation technology; Scheffersomyces stipitis;

    Sammanfattning : Saccharomyces cerevisiae is one of the most well characterized yeast of large industrial interest due to several attractive features such as its capability to efficiently convert glucose into ethanol and carbon dioxide at high flux, its amenability to genetic modification and the presence of extensive knowledge databases. For these reasons, it is often considered a suitable cell factory for the production of different classes of compounds. LÄS MER