Sökning: "lung recruitment"

Visar resultat 1 - 5 av 77 avhandlingar innehållade orden lung recruitment.

  1. 1. Intestinal effects of lung recruitment maneuvers

    Författare :Jonas Claesson; Ola Winsö; Stefan Lehtipalo; Conny Arnerlöv; Björn Biber; Göran Hedenstierna; Petter Aadahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute lung injury; oleic acid lung injury; ischemia; reperfusion injury; swine; mechanical ventilation; lung recruitment; splanchnic circulation; laser Doppler flowmetry; tissue oxygen tension; microdialysis; lactate; glycerol; Anaesthetics and intensive care; Anestesiologi och intensivvård; lungmedicin; Lung Medicine;

    Sammanfattning : Background and aims: Lung recruitment maneuvers (brief episodes of high airway pressure) are a modern treatment alternative to achieve open lung conditions under mechanical ventilation of patients with acute lung injury. It is well known that positive pressure ventilation with high airway pressures cause negative circulatory effects, and that the effects on regional vascular beds can be even more pronounced than the systemic effects. LÄS MER

  3. 2. Titrating Open Lung PEEP in Acute Lung Injury : A clinical method based on changes in dynamic compliance

    Författare :Fernando Suarez Sipmann; Göran Hedenstierna; Hans Hedenström; Stefan Lundin; Uppsala universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; PEEP; open lung; recruitment; dead space; electrical impedance tomography; ARDS.; Medicine; Medicin;

    Sammanfattning : The recognition that supportive mechanical ventilation can also damage the lung, the so called ventilation induced lung injury (VILI), has revived the more than 40 year long debate on the optimal level of PEEP to be used. It is established that the prevention of VILI improves patient outcome and that PEEP exerts protective effects by preventing unstable diseased alveoli from collapsing. LÄS MER

  4. 3. FRC in acute lung injury. Experimental and clinical studies

    Författare :Christian Rylander; Göteborgs universitet; []
    Nyckelord :Airway obstruction; Acute lung injury; Acute respiratory distress syndrome; Attenuation; Computed tomography; End-expiratory lung volume; Functional residual capacity; Gas dilution; Hounsfield unit; Lung volume; Oleic acid; Recruitment; Time constant;

    Sammanfattning : Respiratory failure due to acute lung injury (ALI) of diffuse inflammatory origin is a major cause of respiratory failure treated in intensive care units. In ALI, FRC is reduced by various mechanisms associated with hypoxemia and consolidation of the lung. LÄS MER

  5. 4. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Författare :Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Sammanfattning : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. LÄS MER

  7. 5. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

    Författare :Alf Kozian; Göran Hedenstierna; Thomas Hachenberg; Filip Freden; Sten Walther; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; Medical laboratory science; Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

    Sammanfattning : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. LÄS MER