Sökning: "One-Lung Ventilation"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden One-Lung Ventilation.

  1. 1. The Immune Response to One-Lung Ventilation Clinical and Experimental Studies

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Thomas Schilling; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; One-lung ventilation; open thoracic surgery; ventilation-induced lung injury; alveolar immune response; bronchoalveolar lavage; propofol; desflurane; cytokines; animal model; mRNA; RT-PCR; INTERDISCIPLINARY RESEARCH AREAS Caring sciences Medical laboratory science; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN Vårdvetenskap Medicinsk laboratorievetenskap; anestesiologi; Anaesthesiology;

    Sammanfattning : One-lung ventilation (OLV) as an established procedure during thoracic surgery may be injurious in terms of increased mechanical stress characterised by alveolar cell stretch and overdistension, increased cyclic tidal recruitment of alveolar units, compression of alveolar vessels and increased pulmonary vascular resistance. This may result in ventilation-induced lung injury with pro-inflammatory cytokine production, leukocyte recruitment and neutrophil-dependent tissue destruction. LÄS MER

  2. 2. Pathophysiological and Histomorphological Effects of One-Lung Ventilation in the Porcine Lung

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Alf Kozian; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alveolar Recruitment Manoeuvre; One-Lung Ventilation; Lung Protective Ventilation; Tidal Volume; Computed Tomography; Tidal Recruitment; Animal Model; Open Thoracic Surgery; Ventilation Perfusion Distribution; Single Photon Emission Computed Tomography; Diffuse Alveolar Damage; INTERDISCIPLINARY RESEARCH AREAS Caring sciences Medical laboratory science; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN Vårdvetenskap Medicinsk laboratorievetenskap; Anestesiologi; Anaesthesiology;

    Sammanfattning : Thoracic surgical procedures require partial or complete airway separation and the opportunity to exclude one lung from ventilation (one-lung ventilation, OLV). OLV is commonly associated with profound pathophysiological changes that may affect the postoperative outcome. LÄS MER

  3. 3. Open lung concept in high risk anaesthesia Optimizing mechanical ventilation in morbidly obese patients and during one lung ventilation with capnothorax

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Henrik Reinius; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anaesthesia; mechanical ventilation; atelectasis; morbidly obese; one-lung ventilation; PEEP; recruitment maneuver; spirometry; EIT; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : Formation of atelectasis, defined as reversible collapse of aerated lung, often occurs after induction of anaesthesia with mechanical ventilation. As a consequence, there is a risk for hypoxemia, altered hemodynamics and impaired respiratory system mechanics. LÄS MER

  4. 4. Cardiopulmonary adaption to one-lung ventilation and neoadjuvant therapy during treatment of esophageal cancer

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Clinical Science, Intervention and Technology

    Författare :Mikael Lund; Karolinska Institutet.; Karolinska Institutet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Introduction: Esophagectomy is the main form of curative treatment for esophageal cancer and has a high morbidity rate. Neoadjuvant chemo- (CT) or chemoradiotherapy (CRT) is employed to increase long-term survival. To improve perioperative care the effects of measures taken to improve surgical exposure i.e. LÄS MER

  5. 5. Benefits of Spontaneous Breathing Compared with Mechanical Ventilation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :László Vimláti; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spontaneous breathing; mechanical ventilation; pulmonary shunt; oxygenation; hypoxic pulmonary vasoconstriction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : When spontaneous breathing (SB) is allowed during mechanical ventilation (MV), atelectatic lung areas are recruited and oxygenation improves thereby. Whether unsupported SB at its natural pattern (without PEEP and at low pressure/small tidal volume) equally recruits and improves oxygenation, and if so by which mechanism, has not been studied. LÄS MER