Sökning: "integrins"

Visar resultat 21 - 25 av 124 avhandlingar innehållade ordet integrins.

  1. 21. Signaling capacity of ß2-integrins in relations to neutrophil motility

    Författare :Ragnhild Löfgren; Linköpings universitet; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; INTERDISCIPLINARY RESEARCH AREAS; TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN;

    Sammanfattning : The neutrophil granulocyte is one of the most mobile cell types in the human body and represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulations of the cytoskeleton and thereby cause the cell to move. LÄS MER

  3. 22. The role of 1-intergrins in skeletal muscle differentiation and extracellular matrix assembly

    Författare :Lars Lohikangas; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; β1 Integrins; Matrix Deposition; Skeletal Muscle Cell; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Integrin subunit β1 forms heterodimeric receptors with at least 12 different α-subunits.These integrins are the main cellular receptors for extracellular matrix and they arenecessary for normal development. In this thesis, the effects of lack of integrin subunitβ1 on matrix deposition and on skeletal muscle development were studied. LÄS MER

  4. 23. Cell-matrix interactions in neuronal regeneration : focus on integrins and laminins

    Författare :Stefan Plantman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The central and peripheral nervous system (CNS and PNS, respectively) differ in their ability to regenerate after injury. This difference has been attributed both to intrinsic differences in the properties of the neurons and to the extracellular environment. LÄS MER

  5. 24. Functional and structural characterization of integrins and their ligands ICAM-2, vitronectin and fibronectin in leukocytes

    Författare :Rosalba Salcedo Amaya; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Leukocytes; Adhesion molecules; Integrins; ICAM-2; Vitronectin; Fibronectin.;

    Sammanfattning : Transient adhesion of leukocytes to cells and extracellular matrices is a crucial process in leukocyte physiology. Cell surface adhesion molecules such as integrins and members of the immunoglobulin (Ig) superfamily are involved. LÄS MER

  7. 25. Studies of Mesenchymal Progenitor Cells and Tumour Growth, Integrins and Matrix Metalloproteinases

    Författare :Lars Bryngelsson Ohlsson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Tumour inhibition; cancer; onkologi; cancerology; Cytologi; oncology; Cytology; Biologi; Biology; Medicin människa och djur ; Medicine human and vertebrates ; Integrin matrix metalloproteinase interaction; Immunologi; serologi; transplantation; Proteins; enzymology; Proteiner; enzymologi; serology; Mesenchumal progenitor cells;

    Sammanfattning : In this thesis we characterize the effect of mesenchymal progenitor cells (MPCs) on tumour growth, and show that MPCs can have inhibitory effects on tumour development. We developed a method to subcutaneously transplant tumour cells, cultured in vitro in a pre-formed gelatin matrix, that made it possible to study the early phases of tumour development. LÄS MER