Sökning: "heterogeneous tumors"

Visar resultat 1 - 5 av 88 avhandlingar innehållade orden heterogeneous tumors.

  1. 1. Accurate description of heterogeneous tumors for biologically optimized radiation therapy

    Författare :Johan Nilsson; Bengt Lind; Anders Brahme; Margareta Edgren; Søren Bentzen; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; heterogeneous tumors; radiation therapy; biological optimization; tumor hypoxia; effective radiation sensitivity; effective radiation resistance; Radiation biology; Strålningsbiologi;

    Sammanfattning : In this thesis, a model of tissue oxygenation is presented, that takes into account the heterogeneous nature of tumor vasculature. Even though the model is rather simple, the resulting oxygen distributions agree very well with clinically observed oxygen distributions for most tumors and healthy normal tissues. LÄS MER

  3. 2. Oncolytic Adenovirus Therapy of Neuroendocrine Tumors

    Författare :Justyna Leja; Magnus Essand; Valeria Giandomenico; Akseli Hemminki; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adenovirus; virotherapy; oncolytic virus; neuroendocrine tumors; chromogranin A; somatostatin receptors; microRNA; novel biomarkers; Molecular biology; Molekylärbiologi; Oncology; Onkologi; Virology; Virologi; Tumour biology; Tumörbiologi; Medical Science; Medicinsk vetenskap; Oncology; Onkologi; Medical Virology; Medicinsk virologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Neuroendocrine tumors (NETs), originally described as carcinoids, represent a rare and heterogeneous group of neoplasms associated with intensive secretion of hormones, bioactive peptides and amines. Most of the patients are diagnosed at a late stage of disease, often with liver metastases. LÄS MER

  4. 3. Pathogenetic Mechanisms in Soft Tissue Tumors

    Författare :Elsa Arbajian; Avdelningen för klinisk genetik; []
    Nyckelord :Soft tissue tumors; Sarcomas; Gene fusions; SNP array; Next generation sequencing; Haploidization; Point mutations;

    Sammanfattning : Soft tissue tumors (STT) constitute a heterogeneous group of tumors that arise in tissues of mesenchymal origin. They are currently classified according to morphology and resemblance to normal tissue into over 100 subtypes. LÄS MER

  5. 4. Molecular and Spatial Profiling of Prostate Tumors

    Författare :Emelie Berglund; Joakim Lundeberg; Päivi Östling; KTH; []
    Nyckelord :Bioteknologi; Biotechnology;

    Sammanfattning : Every cancer tumor is unique, with characteristics that change over time. The evolution of a full-blown malignancy from a single cell that gives rise to a heterogeneous population of cancer cells is a complex process. LÄS MER

  7. 5. Novel therapeutic targets in pediatric neural tumors

    Författare :Jelena Milosevic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The embryonal tumors neuroblastoma and medulloblastoma are two of the most common and deadliest tumors in childhood. Both are heterogeneous tumors that arise in the peripheral and central nervous system, respectively. LÄS MER