Sökning: "global methylation"
Visar resultat 16 - 20 av 57 avhandlingar innehållade orden global methylation.
16. Molecular Characterization of Male Breast Cancer
Sammanfattning : Cancer is today a major healthcare problem worldwide. There are many forms of cancer, which is a genetic disease, believed to result from a multistep process with genetic and epigenetic changes accumulating over time. Breast cancer is one of the most common forms of cancer in women, while it is much more rare in men. LÄS MER
17. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota
Sammanfattning : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. LÄS MER
18. DNA methylation and hypomethylating agents in high-risk myelodysplastic syndromes and acute myeloid leukemia
Sammanfattning : Epigenetic alterations are common in cancer. One example is aberrant hypermethylation of the promoters of tumor suppressor genes and hence silencing of gene expression. LÄS MER
19. Genetic Characterization and Identification of Novel Treatment Targets in Anaplastic Thyroid Carcinoma
Sammanfattning : Anaplastic thyroid cancer (ATC) is a rare and highly aggressive thyroid malignancy, usually resistant to conventional therapeutic strategies. The prognosis of ATC is extremely poor with a median survival rate of 6 months. Current treatment therapy includes surgical resection in combination with external radiotherapy and chemotherapy. LÄS MER
20. Behind the scenes of thyroid tumors : underlying genetic mechanisms
Sammanfattning : Thyroid cancer is the most frequently observed malignancy involving endocrine tissues. This group of diseases is also the major cause of death related to neoplasia of the endocrine system. Tumors in the thyroid gland are common in the general population and the majority represents benign follicular adenoma (FTA). LÄS MER