Sökning: "genetic clustering"
Visar resultat 1 - 5 av 84 avhandlingar innehållade orden genetic clustering.
1. Incremental Clustering of Source Code : a Machine Learning Approach
Sammanfattning : Technical debt at the architectural level is a severe threat to software development projects. Uncontrolled technical debt that is allowed to accumulate will undoubtedly hinder speedy development and maintenance, introduce bugs and problems in the software product, and may ultimately result in the abandonment of the source code. LÄS MER
2. Genetic susceptibility to cervical and gastric cancer
Sammanfattning : Cervical and gastric cancer both to a large extent depend on infectious agents. Cervical infection with human papilloma virus increases the risk for cervical cancer substantially, and infection with the bacteria Helicobacter pylori increases the risk for gastric cancer. LÄS MER
3. Exploring genetic heterogeneity in cancer using high-throughput DNA and RNA sequencing
Sammanfattning : High-throughput sequencing (HTS) technology has revolutionised the biomedical sciences, where it is used to analyse the genetic makeup and gene expression patterns of both primary patient tissue samples and models cultivated in vitro. This makes it especially useful for research on cancer, a disease that is characterised by its deadliness and genetic heterogeneity. LÄS MER
4. Methodology and Infrastructure for Statistical Computing in Genomics : Applications for Ancient DNA
Sammanfattning : This thesis concerns the development and evaluation of computational methods for analysis of genetic data. A particular focus is on ancient DNA recovered from archaeological finds, the analysis of which has contributed to novel insights into human evolutionary and demographic history, while also introducing new challenges and the demand for specialized methods. LÄS MER
5. Genetic Aspects of Endocrine Tumorigenesis : A Hunt for the Endocrine Neoplasia Gene
Sammanfattning : Endocrine tumors arise from endocrine glands. Most endocrine tumors are benign but malignant variants exist. Several endocrine neoplasms display loss of parts of chromosome 11 or 18, produce hormones and responds poorly to conventional chemotherapeutics. The multiple endocrine neoplasia syndromes are mainly confined to endocrine tumors. LÄS MER