Sökning: "endocrine tumor"

Visar resultat 11 - 15 av 77 avhandlingar innehållade orden endocrine tumor.

  1. 11. Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

    Författare :Jenny-Maria Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ovarian cancer; gene expression profiling; Lynch syndrome; targeted deep sequencing; chromatin remodeling; molecular subtypes; endocrine receptors; prognostic factors; tumor heterogeneity;

    Sammanfattning : Ovarian cancer is the seventh most common cancer in women globally, with approximately 240,000 new cases annually. Although a rare disease, it is the most lethal gynecologic malignancy. Unspecific symptoms result in late diagnosis and a generally poor prognosis. LÄS MER

  3. 12. Positron Emission Tomography in the Management of Neuroendocrine Tumors

    Författare :Håkan Örlefors; Barbro Eriksson; Mats Bergstrom; Anders Sundin; Karel Pacak; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Neuroendocrine tumor NET ; carcinoid; endocrine pancreatic tumor EPT ; Positron Emission Tomography PET ; serotonin-precursor; 5-hydroxytrytophan 5-HTP ; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Medicin; Medicine;

    Sammanfattning : Neuroendocrine tumors (NET´s) are often characterized by overproduction of peptide hormones. In spite of pronounced clinical symptoms, the tumor lesions can be small and difficult to detect. LÄS MER

  4. 13. Body constitution, statin use, and tumor characteristics. Implications for prognosis

    Författare :Helga Tryggvadottir; Epidemiologi och farmakogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; prognosis; tumor-specific markers; HMG-CoA reductase; aryl hydrocarbon receptor; aromatase; statins; anthropometric factors;

    Sammanfattning : Breast cancer is an important cause of disease-burden and death in women. To prevent over- and undertreatment of breast cancer patients, new prognostic and predictive factors are needed. LÄS MER

  5. 14. Molecular mechanisms of tumor development in hyperparathyroidism

    Författare :Filip Farnebo; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :parathyroid; hyperparathyroidism; MEN 1; FIHP; loss of heterozygosity; comparative genomic hybridization; mutation analysis; in situ hybridization;

    Sammanfattning : Loss of heterozygosity (LOH) analysis and comparative genomic hybridization (CGH) were used in an attempt to identify recurrent chromosomal alterations in different types of parathyroid tumors. These included familial and sporadic, benign and malignant, as well as primary, irradiation associated and secondary tumors. LÄS MER

  7. 15. Endocrine signaling and molecular aberrations in primary hyperparathyroidism

    Författare :Felix Haglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Primary hyperparathyroidism is a common endocrine disorder, characterized by an inappropriate increase in serum parathyroid hormone (PTH) levels. It is most often caused by a single benign parathyroid tumor. LÄS MER