Sökning: "embryonic stem cells"

Visar resultat 21 - 25 av 249 avhandlingar innehållade orden embryonic stem cells.

  1. 21. Human articular chondrocytes. Plasticity and differentiation potentials

    Författare :Tommi Tallheden; Göteborgs universitet; []
    Nyckelord :autologous chondrocyte transplantation; dedifferentiation; redifferentiation; stem; cells;

    Sammanfattning : Articular cartilage has no or very low ability for self-repair and untreated lesions may lead tothe development of Osteoarthritis (OA). One method, which has been proved to result in longterm repair of isolated lesions, is autologous chondrocyte transplantation (ACT). LÄS MER

  3. 22. Stem cells for cardiac regeneration

    Författare :Ivana Bulatović; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recent studies have demonstrated a turnover of cardiomyocytes throughout the adult life. Whether this regenerative potential is due to proliferation and differentiation of resident stem cells or to the dedifferentiation of adult cardiomyocytes remains unclear. LÄS MER

  4. 23. Visualization and manipulation of microRNA in neural cells

    Författare :Rohit Sachdeva; Molekylär neurogenetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microRNA; miRNA; miR-124; miR-9; embryonic stem cells; neural stem cell; cell transplantation; neurogenesis; microglia;

    Sammanfattning : microRNA (miRNA) are small non-coding RNA, 21-23 nucleotides long. miRNA provide a new layer of regulatory control over gene expression programs. It is increasingly evident that miRNA are cell type and tissue specific. Many miRNAs have been identified to be highly abundant in certain regions of the brain. LÄS MER

  5. 24. Protein Damage Control during Embryonic Stem Cell Differentiation: Role of the Proteasome

    Författare :Malin Hernebring; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Embryonic Stem Cells; Proteasome; Protein Carbonylation; Advanced Glycation End products; Cell Differentiation; Oxidative stress; Aging; RNAi;

    Sammanfattning : During the lifespan of organisms ranging from yeast to humans, there is an accumulation of macromolecular damage. However, these organisms produce youthful progeny with low damage levels. This thesis focuses on how this is accomplished. LÄS MER

  7. 25. Molecular mechanisms of embryonic stem cell pluripotency: transcription, telomere maintenance and proliferation

    Författare :Dzeneta Vizlin-Hodzic; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; embryonic stem cells; Oct4; SAF-A; Brg1; Tpt1; Npm1; transcriptional regulation; cell proliferation; shelterin;

    Sammanfattning : Somatic cell nuclear transfer and generation of induced pluripotent stem cells provide potential routes towards generation of patient specific embryonic stem (ES) cells. These procedures require induction of Oct4 gene expression, high telomerase activity and specific cell proliferation, characteristics shared with cancer stem cells. LÄS MER