Sökning: "embryonic stem cells"
Visar resultat 1 - 5 av 248 avhandlingar innehållade orden embryonic stem cells.
1. Human embryonic stem cells for bone engineering applications
Sammanfattning : The human skeleton represents the supporting structure of the organism and accounts for about 20 percent of the total body mass. Despite its intrinsic capacity to regenerate and self-repair, this ability is limited and repair therapies are needed in a large number of clinical cases. LÄS MER
2. Generation of Dopaminergic Neurons from Human Embryonic Stem Cells
Sammanfattning : Since the first successful derivation of human embryonic stem cells (hESC), rapid progress has been attained in the development of strategies in differentiation of these cells into various neural lineages, with the fundamental objective of using these cells for replacement and repair of damaged neuronal circuits in the central nervous system (CNS). Of particular interest are midbrain dopaminergic (mDA) neurons, which play a central role in regulation of voluntary movement. LÄS MER
3. Towards Generation of Human Hematopoietic Stem Cells from Pluripotent Stem Cells
Sammanfattning : There is a pressing need for compatible Hematopoietic Stem Cells (HSCs), in high quantities and of good clinical quality, to ensure optimal treatment for patients with various blood malignancies. Pluripotent Stem Cells (PSCs) have the potential to be a source for generating HSCs. LÄS MER
4. Genetic Sex Differences in Early Human Neuronal Development : An Investigation in Embryo Tissue and Embryonic Stem Cells
Sammanfattning : Sex differences in the human body affect many different organs and tissues, some of them have an effect on the human brain and its development. In the developing nervous system, sex differences can bias the number or functionality of neurons, glial cells or synapses. As a result, neural networks might develop with a sex-specific bias. LÄS MER
5. Pluripotent Stem Cells of Embryonic Origin : Applications in Developmental Toxicology
Sammanfattning : General toxicity evaluation and risk assessment for human exposure is essential when developing new pharmaceuticals and chemicals. Developmental toxicology is an important part of this risk assessment which consumes large resources and many laboratory animals. LÄS MER