Sökning: "dorsal striatum"
Visar resultat 16 - 20 av 35 avhandlingar innehållade orden dorsal striatum.
16. Long-term neurogenesis after stroke in the adult rat brain
Sammanfattning : Stroke is a leading cause of death and disability for which there is no treatment for functional recovery. Following stroke, striatal neurogenesis is increased, with newly formed neuroblasts migrating towards the damage. This response has so far been considered acute and transient. LÄS MER
17. Stress, Drugs and Neuroscience : Neurobiological Effects of Social Stressors and Drug Exposure in Young and Adolescent Rats
Sammanfattning : Experiences early in life or during adolescence modulate neuronal networks in the immature brain and consequently lay the foundation for future susceptibility or resilience towards psychiatric disorders. The objective in this thesis is to understand, in part, how the surrounding environment shapes the brain of a young individual. LÄS MER
18. Exploring the miRNA profile of medium spiny neurons using retrograde transport in rats
Sammanfattning : The basal ganglia play an essential role in movement selection and control. It is therefore not surprising that they are central to neurodegenerative diseases like Parkinson’s disease and Huntington’s disease. LÄS MER
19. Early Environment, Adolescent Alcohol Drinking and Neurobiological Responses to Drugs
Sammanfattning : Genes and environment interact to determine an individual’s vulnerability or resilience to several psychiatric disorders, including alcohol use disorder (AUD). Alcohol use is often initiated during adolescence and early onset drinking is associated with increased risk for later AUD. LÄS MER
20. The hippocampal opioid system : role in spatial learning
Sammanfattning : The main aim of the present thesis was to study the role of the endogenous hippocampal opioid system, and in particular, the role of dynorphin B and nociceptin, in spatial learning. The effects of bilateral infusion (using chronic cannulae) of dynorphin B into the dorsal hippocampus (CA3-region), an area containing a high number of dynorphin-containing neurons, were examined in the Morris swim-maze, a spatial task dependent on hippocampal functioning. LÄS MER