Sökning: "dorsal striatum"

Visar resultat 21 - 25 av 35 avhandlingar innehållade orden dorsal striatum.

  1. 21. PET studies of the serotonin system in relation to behavioral phenotypes in psychiatry

    Författare :Ämma Tangen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Behavioral phenotypes beyond core symptoms of diagnoses have become an area of high interest in psychiatric research. All major psychiatric diagnoses are associated with deficits in cognitive function, including impairments in social abilities, which contribute to great suffering and have a negative impact on the everyday life. LÄS MER

  3. 22. Dopamine D2 receptor G protein coupling and it's regulation

    Författare :Anton Terasmaa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dopamine; D2 receptor; G protein; supersensitivity; 6-hydroxydopamine; [3 S]GTP-gamma-S; radioligand binding;

    Sammanfattning : Dopamine (DA) receptors belong to the superfamily of G protein coupled receptors. The D2 DA receptor is negatively coupled with adenylate cyclase via pertussis toxin sensitive (Gi/o) G proteins. LÄS MER

  4. 23. The neural control of rhythmic motor sequences

    Författare :Anke Ninija Karabanov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Sequence learning is one of the most important functions of the motor system since almost every advanced motor skill consists of many component movements that need to be executed in sequential order. For successful performance both, the correct serial order of movements and adequate timing are of importance. LÄS MER

  5. 24. Molecular and functional neuroanatomy of mood disorder circuits

    Författare :Antje Märtin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The ability to interpret and react to external stimuli is essential for survival. An organism has to be able to predict a favorable outcome, and, more importantly, a non-favorable one that could mean danger for life. LÄS MER

  7. 25. Molecular mechanisms underlying the actions of psychoactive drugs in the basal ganglia : focus on cannabinoids and morphine

    Författare :Anders Borgkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is centered on the identification of the molecular mechanisms involved in the psychomotor effects of cannabinoids and morphine. These drugs share the ability of acting at the level of the basal ganglia, a group of subcortical structures involved in the control of locomotion, as well as in cognitive and motivational aspects of motor function. LÄS MER