Sökning: "clopidogrel"

Visar resultat 11 - 15 av 31 avhandlingar innehållade ordet clopidogrel.

  1. 11. Platelet Inhibition and Bleeding in Coronary Artery Bypass Surgery

    Författare :Ulrica Alström; Elisabeth Ståhle; Ulf Schött; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bleeding; cardiac surgery; platelet inhibition; re-exploration; cost analysis; Anaesthetics and intensive care; Anestesiologi och intensivvård; Thoraxkirurgi; Thorax Surgery; Anaesthesiology and Intensive Care; Anestesiologi och intensivvård;

    Sammanfattning : A substantial number of patients undergoing cardiac surgery are on dual anti-platelet treatment with clopidogrel and aspirin. A disadvantage with this treatment is increased risk of bleeding. Bleeding is a complication of major concern associated with adverse outcome for the patient and increased hospital resource utilization. LÄS MER

  3. 12. Atrial Fibrillation in the setting of Coronary Artery Disease : Risks and outcomes with different treatment options

    Författare :Gorav Batra; Jonas Oldgren; Gunnar Gislason; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; coronary artery disease; acute coronary syndrome; myocardial infarction; percutaneous coronary intervention; coronary artery bypass grafting; antithrombotic therapy; angiotensin-converting enzyme inhibitors; angiotensin II receptor blockers; epidemiology; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Coronary artery disease (CAD) is the leading cause of mortality worldwide and atrial fibrillation (AF) is a prevalent arrhythmia associated with increased risk of mortality and morbidity. Despite improved outcome in both diseases, there is a need to further describe the prevalence, outcome and management of CAD in patients with concomitant AF. LÄS MER

  4. 13. Platelet function and thrombin generation in ischemic stroke : clinical correlates and prognostic importance

    Författare :Annika Lundström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Platelet function is central to atherothombotic diseases and antiplatelet agents prevent non-cardioembolic ischemic stroke (IS). Individual differences in platelet reactivity may limit the response to antiplatelet treatment, leading to so-called high on-treatment platelet reactivity (HPR). LÄS MER

  5. 14. Platelets and the inflammatory response in coronary heart disease

    Författare :Petter Järemo; Frank Brosstad; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The thesis investigates a new invented computerised apparatus suitable for determining platelet density distribution and peak platelet density in undisturbed linear Percoll™ gradients. The device measures light transmission through test tubes containing density-separated platelets. LÄS MER

  7. 15. Pathophysiological, Inflammatory and Haemostatic Responses to Various Endotoxaemic Patterns : An Experimental Study in the Pig

    Författare :Miklós Lipcsey; Mats Eriksson; Jan Sjölin; Anders Larsson; Anders Bengtsson; Uppsala universitet; []
    Nyckelord :Anaesthesiology and intensive care; sepsis; animal model; cytokines; isoprostanes; endotoxic shock; pig; Anestesiologi och intensivvård;

    Sammanfattning : Septic shock is frequently seen in intensive care units and is associated with significant mortality. Endotoxin – a major mediator of the pathophysiologic responses – is released during lysis of Gram-negative bacteria. These responses can be mimicked in the endotoxaemic pig. LÄS MER