Sökning: "clopidogrel"

Visar resultat 16 - 20 av 31 avhandlingar innehållade ordet clopidogrel.

  1. 16. Influence of chronic kidney disease on presentation, treatment and outcome in patients with coronary artery disease

    Författare :Robert Edfors; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background. About one third of patients with myocardial infarction (MI) have renal dysfunction (RD). Concomitant coronary artery disease (CAD) and RD is accompanied by a markedly higher risk of death and subsequent cardiovascular (CV) events. LÄS MER

  3. 17. Point-of-care testing of platelet P2Y12-inhibition in patients with acute coronary syndrome

    Författare :Manne Holm; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The point-of-care platelet function test Plateletworks® has been shown to identify patients with high platelet aggregation despite P2Y12 inhibition, also known as high-on-treatment platelet reactivity (HPR), who have increased risk for ischemic cardiovascular events. However, this platelet function assay has not been sufficiently validated. LÄS MER

  4. 18. Platelet Adhesion to Proteins in Microplates : Applications in Experimental and Clinical Research

    Författare :Andreas Eriksson; Per Whiss; Håkan Wallén; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelets; platelet adhesion; platelet assay; synergistic activation; thrombosis; anti-platelet treatment; Pharmacology; Farmakologi;

    Sammanfattning : Platelets are crucial for prevention of blood loss after vessel injury. Platelet adhesion to disrupted vessel walls is mediated by receptors such as the GPIb-IX-V complex that binds von Willebrand factor and the collagen-binding integrin α2β1. LÄS MER

  5. 19. Secondary prevention after acute coronary syndrome : antiplatelet therapy and risk factor control

    Författare :Robin Henriksson; Thomas Mooe; Fredrik Björklund; Stefan James; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; secondary prevention; myocardial infarction; ischemic stroke; antiplatelet therapy; risk factors; randomized controlled trial; cardiovascular disease; hjärt- och kärlforskning; kardiologi; Cardiology;

    Sammanfattning : Background: One of the leading causes of death and disability worldwide is cardiovascular disease (CVD), including acute myocardial infarction (AMI). Despite improvements in medical treatment, management, and care over the years and the halving of mortality in recent decades, there is considerable room for improvement. LÄS MER

  7. 20. Coagulation during and after cardiopulmonary bypass with focus on heparin, protamine, aprotinin and platelet function

    Författare :Gunilla Kjellberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Heparin and protamine dosing for anticoagulation during cardiopulmonary bypass (CPB) and its reversal after CPB, respectively, is usually given according to body weight. Excess protamine may impair coagulation. The HeProCalc algorithm calculates heparin and protamine doses during the procedure. LÄS MER