Sökning: "clopidogrel"

Visar resultat 6 - 10 av 31 avhandlingar innehållade ordet clopidogrel.

1. 6. Novel Agonists and Antagonists of Platelet Receptors

   Författare :Carl Högberg; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Platelets; P2Y12; SUCNR1; FPP; hypothermia;

   Sammanfattning : Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. LÄS MER

3. 7. Experimental and Clinical Studies on Platelet Receptors in Cardiovascular Disease

   Författare :Oscar Braun; Kardiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; inflammation; athersosclerosis; platelets; thrombosis; Cardiovascular system; Kardiovaskulära systemet;

   Sammanfattning : The crucial role of platelets in maintaining primary hemostais has been evident for a long time and there is now also mounting evidence for their involvement in inflammation. In combination with aspirin, inhibition of the platelet P2Y12 ADP receptor with clopidogrel has become a cornerstone in the antiplatelet in acute coronary syndromes. LÄS MER

4. 8. Studies on platelet function and microvesicles in acute coronary syndrome

   Författare :Sam Kafian; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : INTRODUCTION: The cornerstone of treatment of acute coronary syndrome (ACS) is percutaneous coronary intervention (PCI) and dual antiplatelet therapy (DAT) with aspirin and the ADP-receptor inhibitor clopidogrel. However, some ACS patients will suffer from recurrent cardiovascular events, and it has been shown that this may partly be due to an insufficient antiplatelet response to DAT. LÄS MER

5. 9. Platelet Inhibition and Bleeding Complications in Cardiac Surgery Patients - Clinical and experimental studies

   Författare :Emma C. Hansson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acute coronary syndrome; Bleeding complications; Cardiac surgery; Platelet aggregation inhibitors; Platelet transfusion;

   Sammanfattning : BACKGROUND AND OBJECTIVE Dual antiplatelet therapy (DAPT) with acetylsalicylic acid and a P2Y12 inhibitor (clopidogrel, ticagrelor, or prasugrel) reduces thrombotic events in patients with acute coronary syndrome (ACS), but it is also associated with an increased risk of bleeding complications. The aim of this project was to investigate the prevalence and effects of platelet inhibition in the context of cardiac surgery, the bleeding problems that may occur, and treatment of bleeding complications. LÄS MER

7. 10. Platelet Inhibition, Revascularization, and Risk Prediction in Non-ST-elevation Acute Coronary Syndromes

   Författare :Daniel Lindholm; Stefan James; Christoph Varenhorst; James de Lemos; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coronary artery disease; myocardial infarction; acute coronary syndrome; non-ST-elevation acute coronary syndrome; P2Y12 inhibitors; ticagrelor; biomarkers; revascularization; percutaneous coronary intervention; risk prediction; Cardiology; Kardiologi;

   Sammanfattning : Cardiovascular disease is the leading cause of death worldwide and ischemic heart disease is the most common manifestation. Despite improved outcomes during the last decades, patients with acute coronary syndromes (ACS) are still at substantial risk of recurrent ischemic events and mortality. LÄS MER