Sökning: "cholesterol absorption"

Visar resultat 11 - 15 av 22 avhandlingar innehållade orden cholesterol absorption.

  1. 11. Studies on the regulatory role of cholic acid in cholesterol metabolism

    Författare :Charlotte Murphy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol is essential for normal growth and development in both man and mouse. However, excess cholesterol can be harmful leading to diseases such as atherosclerosis and gallstones. Once formed cholesterol cannot be catabolised by the body and must therefore be converted to other compounds for excretion. LÄS MER

  3. 12. Studies on the effects of thyroid hormone on cholesterol and lipoprotein metabolism

    Författare :Ylva Bonde; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Elevated plasma lipids, particularly cholesterol within low density lipoproteins, is an important risk factor for developing atherosclerosis which can cause angina pectoris, myocardial infarction, and stroke. Thyroid hormone (TH) has a strong influence on lipid metabolism and the aim of this thesis was to gain more insight into how TH modulates cholesterol and lipoprotein metabolism. LÄS MER

  4. 13. Functional study of nuclear receptors and bile acids in the modulation of cholesterol homeostasis

    Författare :Xiaoli Hu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cholesterol carries multiple biological functions in the body, and imbalanced cholesterol metabolism leads to atherosclerosis and cardiovascular diseases. The present thesis aims to extend the knowledge of cholesterol metabolic regulation mediated by nuclear receptor LXRs and bile acids, two major players in the homeostasis of body cholesterol. LÄS MER

  5. 14. Observations on essential biochemical data profile in connection with restorative proctocolectomy in humans : vitamin B12 and fat absorption cited

    Författare :Amosy Ephreim M'Koma; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : PATIENTS: The material includes 99 patients who consecutively received handsawn pouch and ileoanal anastomosis, after mucosectomy. Sixty-five patients were men and forty-four were women. The mean-age was 31.4 (range 17-59) years. LÄS MER

  7. 15. Studies on lipoprotein metabolism and atherogenesis

    Författare :Katharina Slätis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ApoA1; ApoB; ApoE; atherosclerosis; bile acids; cholic acid; cholesterol; cholesterol absorption; CYP7A1; CYP8B1; dexamethasone; GC-1; PAI-1; thyroid hormone receptor; very low density lipoprotein receptor;

    Sammanfattning : Atherosclerosis is the primary cause of cardiovascular events such as angina pectoris and myocardial infarction, which together with stroke are responsible for around 50% of all deaths in the United States and Europe. Usually atherosclerosis develops over several decades and leads to a progressive narrowing of arterial vessels. LÄS MER