Sökning: "chiral recognition"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden chiral recognition.
1. Chiral recognition on cellulases : The active sites of the enzymes are involved
Sammanfattning : Two cellobiohydrolases (CBH I and CBH II) and endoglucanase I (EG I) fromTrichoderma reesei, and CBH 58 from Phanerochaete chrysosporium were immobilized onsilica as chiral stationary phases (CSPs) in HPLC for enantioseparation of a group ofpharmaceutical compounds. CBH I and CBH 58 wore excellent chiral selectors for β-adrenergic blocking agents, whereas CBH II displayed good enantioselectivity for someother compounds The CBHs share the common feature that their active sites are located intunnels. LÄS MER
2. Chiral Recognition by Means of Mass Spectrometry
Sammanfattning : This thesis is based on experimental studies of chiral ions in gas-phase. Electrospray ion source platform (Stockholm University) and commercially available Quadrupole Time-of-Flight mass spectrometer have been used in our studies. LÄS MER
3. Interactions of chiral ions and molecules in gas phase : Towards an understanding of chiral recognition mechanism
Sammanfattning : This thesis comprises the research related to interactions of enantiopure amino acids with chiral and achiral molecules in gas phase. The investigation of the mechanism responsible for chiral discrimination is of the special interest in this work. LÄS MER
4. Molecular Recognition Studies Based on Imprinting Technology
Sammanfattning : In this thesis, I have focused on five main research areas: 1). A new type of imprinted polymer has been developed, namely the amide MIP. The amide functional monomers showed better hydrogen bonding capabilities in polar organic solvents and the resulting polymers exhibited good enantiomeric recognition properties in organic media. LÄS MER
5. Enantioselective Binding of Designed Propranolol Analogues to the Cellobiohydrolase Cel7A
Sammanfattning : This thesis describes the affinity and enantiomeric selectivity of the cellobiohydrolase Cel7A (isolated from Hypocrea jercorina). The chiral recognition of the enzyme has been studied with respect to amino alcohols and new ligands have been designed, based on the structure of the common ?-blocker propranolol. LÄS MER