Sökning: "challenge models"

Visar resultat 1 - 5 av 622 avhandlingar innehållade orden challenge models.

  1. 1. Challenge models and biomarkers of human intestinal barrier function

    Författare :María Fernanda Roca Rubio; Julia König; Robert J Brummer; Richard Forsgård; Kaatje Lenaerts; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bacterial translocation; biomarkers; challenge models; intestinal barrier function; intestinal permeability; irritable bowel syndrome; physiological stress; psychological stress;

    Sammanfattning : The intestinal barrier is an essential component in maintaining human health, and several diseases and disorders have been associated with a disrupted intestinal barrier function. To evaluate the efficacy of different interventions intended to strengthen intestinal barrier function, there is a need for both appropriate challenge models as well as easily accessible biomarkers. LÄS MER

  2. 2. Authority-based argumentative strategies : Three models for their evaluation

    Författare :Taeda Jovičić [Tomic]; Krister Segerberg; Frederick Stoutland; Douglas Walton; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Philosophy; argumentative strategies; reasoning and social aspects of argumentative activities; argumentative groups; audience groups; acceptability; effectiveness; challenge; evaluation; authority; dialectic; rhetoric; pragma-dialectics; logic of dialogue; profiles of dialogue; Filosofi; Philosophy subjects; Filosofiämnen; Theoretical Philosophy; Teoretisk filosofi;

    Sammanfattning : This dissertation is on argumentative strategies based on authority. In its first half, three of the most elaborate and influential approaches in argumentation theory, related to the models developed in this work, are analyzed: Douglas Walton's dialectical frame for analysis of arguments from expert opinion; Frans van Eemeren and Peter Houtlosser's pragma-dialectical approach to strategic maneuvering in argumentation; the concept of strategy used in Else Barth and Erik Krabbe's formal dialectics. LÄS MER

  3. 3. Collaboration and Coordination Challenges in Patient-Centered Care : Models and Informaion Services

    Författare :Monica Winge; Benkt Wangler; Paul Johannesson; Fredrik Karlsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; patient-centered care; healthcare; social care; home care; collaboration; coordination; care processes; processes coordination; multi-sectoral collaboration; communication; information models; information services; management; Computer and Systems Sciences; data- och systemvetenskap;

    Sammanfattning : This thesis reports on research focuses on how to deal with the fact that the organization and processesof today’s health and social care are becoming ever more complex as a consequence of societal trends, including an aging population and an increased reliance on care at home. The overall research goal is to suggest ways in which IT-based solutions can enable and leverage collaboration and coordination insituations where a co-morbid patient is subject to care delivered simultaneously by several different professionals and organizations. LÄS MER

  4. 4. Towards Accurate and Reliable Deep Regression Models

    Författare :Fredrik K. Gustafsson; Thomas B. Schön; Martin Danelljan; Søren Hauberg; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Machine Learning; Deep Learning; Regression; Probabilistic Models; Energy-Based Models; Uncertainty Estimation; Machine learning; Maskininlärning;

    Sammanfattning : Regression is a fundamental machine learning task with many important applications within computer vision and other domains. In general, it entails predicting continuous targets from given inputs. LÄS MER

  5. 5. New targeted therapies for malignant neural tumors : From systematic discovery to zebrafish models

    Författare :Elin Almstedt; Sven Nelander; Rogier Versteeg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neuroblastoma; glioblastoma; data integration; zebrafish models; precision medicine; Oncology; Onkologi; Medical Cell Biology; Medicinsk cellbiologi; Medical Informatics; Medicinsk informatik; Farmakokinetik och läkemedelsterapi; Pharmacokinetics and Drug Therapy; Molekylär medicin; Molecular Medicine;

    Sammanfattning : Cancers in the neural system presents a major health challenge. The most aggressive brain tumor in adults, glioblastoma, has a median survival of 15 months and few therapeutic options. High-risk neuroblastoma, a childhood tumor originating in the sympathetic nervous system, has a 5-year survival under 50%, despite extensive therapy. LÄS MER