Sökning: "virus-host cell interaction"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden virus-host cell interaction.

  1. 1. Rift Valley fever : consequences of virus-host interactions

    Författare :Maria Baudin; Magnus Evander; Clas Ahlm; Göran Bucht; Tomas Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rift Valley fever; Rift Valley fever virus; viral haemorrhagic fever; miscarriage; entry; charge; carbohydrates; high-throughput screening; antiviral; cell-based assay; medicinsk virologi; Medical Virology;

    Sammanfattning : Rift Valley fever virus (RVFV) is a mosquito-borne virus which has the ability to infect a large variety of animals including humans in Africa and Arabian Peninsula. The abortion rate among these animals are close to 100%, and young animals develop severe disease which often are lethal. LÄS MER

  3. 2. Virus Host Interactions in SARS Coronavirus Infection

    Författare :Vithiagaran Gunalan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The global outbreak of Severe Acute Respiratory Syndrome which began in 2002 and ended in 2003 resulted in over 8000 cases in 29 countries, causing an atypical pneumonia which resulted in a case fatality rate of ~10%. The etiological agent of this disease was found to be a novel coronavirus dubbed SARS Coronavirus (SARS-CoV). LÄS MER

  4. 3. The Epstein-Barr nuclear antigens 1 & 5; Study of virus-host cellular protein interactions

    Författare :Alma Forsman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; EBNA1; EBNA5; EBNA-LP; cellular network; virus-host protein interactions;

    Sammanfattning : The Epstein-Barr virus (EBV) is the causative agent or cofactor in the aetiology of several human malignancies such as Burkitt’s lymphoma, Hodgkin’s disease, nasopharyngeal carcinoma (NPC) and lymphoproliferative disorder in immunocompromised patients. EBV is a lymphotropic γ-herpes virus infecting more than 90 percent of the population worldwide. LÄS MER

  5. 4. Dissection of virus-host cell interactions in the early response to infection

    Författare :Marc D Panas; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Stress granules (SG) are dynamic RNA/protein assemblies in the cytoplasm of the cell, formed under conditions of oxidative stress, heat shock or viral infections. These stress conditions trigger a sudden translational arrest, leading to a rapid switch of translation from housekeeping genes to stress-related factors. LÄS MER

  7. 5. Analysis of PDGF receptor internalization and signaling using proximity ligation assays

    Författare :Marie Rubin Sander; Ola Söderberg; Cristina Al-Khalili Szigyarto; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGFRβ; dynamin; proteolytic cleavage; signaling; internalization; protein-protein interaction; short linear motif; viral hijack; in situ PLA; Molboolean;

    Sammanfattning : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. LÄS MER