Sökning: "caudate nucleus"

Visar resultat 1 - 5 av 24 avhandlingar innehållade orden caudate nucleus.

  1. 1. Mammalian brain acetylcholinesterase : a study of its solubilization, purification, molecular state and interactions with cholinergic ligands including an endogenous modulator

    Författare :Bertil Niklasson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity chromatography; caudate nucleus; acetylcholinesterase; tetracaine; décaméthonium; d-tubocurarine; edrophonium; fluoride ion; hysteric properties; endogenous ligands to AChE;

    Sammanfattning : Membrane bound AChE from calf brain caudate nucleus was solubilized by use of ion-free media in presence of 10~ M EDTA and 10“5M tetracaine. The irreversible release of AChE was more effectively inhibited by divalent ions compared to monovalent ions added to the medium. LÄS MER

  3. 2. Brains, genes and environment of suicide attempters

    Författare :Fredrik Vang; Lund Psykiatri; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; suicide; attempted suicide; self-injury; factor analysis; psychometrics; suicide assessment scale; cortisol; hpa-axis; hypothalamic-pituitary-adrenal axis; depression; adjustment disorder; serotonin transporter; 5HTTLPR; adversities; negative life events; globus pallidus; caudate nucleus; SPECT; MRI; volumetry; dichotic listening; brain lateralization; functional brain asymmetry;

    Sammanfattning : Identification of symptoms or biological abnormalities that predispose to suicide or identifies specific vulnerabilities, may one day improve allocation of resources or help tailor treatment to the patient. Paper I: We compared the predictive value of symptom-oriented questions against direct questions about suicidality in assessing risk for suicide attempts. LÄS MER

  4. 3. Studies on Premenstrual Dysphoria

    Författare :Olle Eriksson; Tord Naessén; Bo Söderpalm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrics and gynaecology; premenstrual dysphoria; PMDD; premenstrual syndrome; estrogen challenge test; gonadotropin feedback response; LH; FSH; neuroendocrine regulation; buspirone; nefazodone; PCO; testosterone; irritability; depressed mood; bloating; visual analogue scale; VAS; 11C-5-hydroxytryptophan; positron emission tomography; right caudate nucleus; Obstetrik och kvinnosjukdomar; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Premenstrual dysphoria, so severe that it affects the lives of the women afflicted, is the condition studied in this thesis. Physiological and pharmacological mechanisms of pathogenetic relevance were investigated. LÄS MER

  5. 4. Dopamine receptors in the rat brain

    Författare :Mi Hillefors-Berglund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Dopamine D2 receptors; Dopamine D3 receptors; Rat; Autoradiography; [3H]7-OH-DPAT; [3H]PD 128907; Caudate-putamen; Subcortical limbic area; Islands of Calleja; CGS 21680; Toluene; Neurotensin; Asphyxia; Aging; Magnesium; GTP;

    Sammanfattning : Dopamine receptors belong to a large superfamily of G protein-coupled receptors and consist of the D1, D2, D3, D4, and D5 receptors. The D2, D3, and D4 receptors belong to the D2 receptor family which is characterized by having a large third cytoplasmic loop and a short C-terminus projecting into the cytosol, and by inhibiting the enzyme adenylyl cyclase. LÄS MER

  7. 5. Magnetic resonance imaging techniques for diagnostics in Parkinson's disease and atypical parkinsonism

    Författare :Henrik Sjöström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Parkinson’s disease (PD) is a neurodegenerative disease characterized by rigidity, hypokinesia, tremor and postural instability. PD is a clinical diagnosis based on neurological examination, patient history and treatment response. LÄS MER