Sökning: "calcium binding protein 4"

Visar resultat 1 - 5 av 55 avhandlingar innehållade orden calcium binding protein 4.

  1. 1. Studies of calcium binding proteins 1 and 2 and protein kinase CK2

    Författare :Inger Janson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; calcium binding protein 1; calcium binding protein 2; calcium binding protein 4; erd2receptor; protein kinase CK2; endoplasmic reticulum; Golgi; microsomes; heparin; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Sammanfattning : The endoplasmic reticulum (ER) is a major intracellular compartment of eukaryotic cells and is the site of the synthesis and post-translational modification of both secretory and membrane glycoproteins. Upon cell rupture vesicles of several kinds are formed from cell membranes, mainly derived from ER and are called microsomes. LÄS MER

  3. 2. Protein Interactions: Electrostatics and Ligand Binding

    Författare :Ingemar André; Biofysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biophysics; Molekylär biofysik; secondary structure formation; protein GB1; pKa values; pH stability; NMR; electrostatic interactions; M proteins; calbindin D9k; calcium binding; cooperativity; calmodulin; calbindin D28k;

    Sammanfattning : This thesis deals with Ca2+ binding to proteins, electrostatic interactions in and between proteins as well as inter- and intramolecular interactions. A computer program was developed to determine Ca2+ binding constants from experimental titration data of proteins. LÄS MER

  4. 3. Calcium-dependent Affinity Domains for the Purification of Antibodies and Antibody Fragments

    Författare :Julia Scheffel; Sophia Hober; Alois Jungbauer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Antibodies; Antibody fragments; Biomanufacturing; Protein purification; Protein engineering; Protein A; ZCa; Calcium; Mild elution; Bioteknologi; Biotechnology;

    Sammanfattning : Antibodies are essential proteins in both our bodies and biotechnological research, and hold outstanding therapeutic value. The market for antibody-based therapeutics has grown exponentially during the last decades, owing to several advantages over small molecule drugs, such as fewer undesirable side effects associated with a higher target specificity. LÄS MER

  5. 4. The influence of adhesion molecules on binding and protein organization in cell contacts

    Författare :Tommy Dam; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T cell; SLBs; Calcium Signaling; TIRF microscopy; Two-Dimensional affinity; Protein Segregation; Protein Organization; Protein Height;

    Sammanfattning : Interactions between immune cells such as T cells and antigen-presenting cells (APCs) are integral for mounting an adaptive immune response. The interaction between the T cell receptor (TCR) and the antigen-presenting major histocompatibility complex (pMHC) on a contacting T cell and APC, is widely accepted to be the key interaction. LÄS MER

  7. 5. Calreticulins- Calcium-Binding Proteins with Functional Diversity and Evolutionary Duality

    Författare :Staffan Persson; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant biochemistry; plant; isoforms; evolution; diversity; differential regulation; chaperone; calnexin; calmegin; calcium; Arabidopsis; calreticulin; Växtbiokemi;

    Sammanfattning : Calreticulin is a multifunctional protein mainly localized in the endoplasmic reticulum in eukaryotic organisms, except yeasts. The protein comprises three distinct regions: the N-terminal N domain, the C-terminal C domain, and the central P domain, reflecting the functional diversity of calreticulin. LÄS MER