Sökning: "biomarker"

Visar resultat 36 - 40 av 777 avhandlingar innehållade ordet biomarker.

  1. 36. Interleukin-6 Signaling Pathways in Human Vascular Endothelial Cells : Molecular Mechanisms and Associations to Atherosclerosis

    Författare :Mulugeta Melkie Zegeye; Liza Ljungberg; Allan Sirsjö; Ashok K Kumawat; Magnus Grenegård; Stefan Rose-John; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HUVECs; Angiogenesis; Laminins; Transmigration; Biomarker; Cytokine; Inflammation; Myocardial infarction;

    Sammanfattning : Interleukin-6 is pleotropic cytokine produced by several types of cells including endothelial cells (ECs). IL-6 acts on target cells via two major signaling mechanisms known as classic signaling and trans-signaling. LÄS MER

  3. 37. A Gill Filament EROD Assay : Development and Application in Environmental Monitoring

    Författare :Maria Jönsson; Ingvar Brandt; Björn Brunström; Kristian Ingebrigtsen; Håkan Olsén; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; aquatic; benzo[a]pyrene; biomarker; CYP1A; environmental monitoring; EROD; fish; gill; indigo; PCB; Biologi; Biology; Biologi;

    Sammanfattning : A gill filament-based assay for the cytochrome P450 1A (CYP1A)-catalysed activity ethoxyresorufin O-deethylase (EROD) was developed in rainbow trout (Oncorhynchus mykiss) and applied to Atlantic salmon (Salmo salar), Arctic charr (Salvelinus alpinus), Atlantic cod (Gadus morhua), saithe (Pollachius virens), and spotted wolffish (Anarhichas minor). Exposure to waterborne β-naphthoflavone (βNF; 10-6 M) induced branchial EROD activity in all species but the spotted wolffish. LÄS MER

  4. 38. Proteomic profiling of bacterial host adaptation : Racing the Red Queen

    Författare :Ola Kilsgård; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteomics; Mass Spectrometry; Systems biology; Biomarker; Host adaptation; Bacteria; Streptococcus pyogenes;

    Sammanfattning : Despite the discovery of antibiotics almost a century ago, infectious diseases continue to be a substantial cause of human mortality and morbidity worldwide, especially in developing countries. The adverse affects of infectious diseases are thought to increase over the coming years as the widespread misuse of antibiotic leads to the emergence of strains for which current therapies are ineffective. LÄS MER

  5. 39. Maternal smoking during pregnancy - Long-term health effects in the offspring

    Författare :Kristina Mattsson; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Maternal smoking during pregnancy; Medical Birth Register; long-term health effects; register validation; biomarker;

    Sammanfattning : Globally, around 10 % of women smoke during pregnancy today. It is known that pregnancy smoking increases the risk of adverse short-term health effects in the offspring, such as preterm birth, low birthweight and spontaneous abortion. Less is known about whether any adverse health effects persist until adulthood. LÄS MER

  7. 40. New Prognostic Markers in Stage III Serous Ovarian Adenocarcinomas

    Författare :Karolina Partheen; Göteborgs universitet; []
    Nyckelord :Ovarian cancer; Biomarker; Prognostic factors; Integrin beta 3;

    Sammanfattning : Ovarian carcinoma is the fifth most common cause of cancer death in Swedish women. Patients with advanced-stage disease respond differently to treatment, and the clinical outcome is difficult to predict for an individual patient. LÄS MER