Sökning: "analytical method"

Visar resultat 1 - 5 av 1238 avhandlingar innehållade orden analytical method.

  1. 1. Organophosphates and phthalates in air and dust from indoor environments : Method development and applied measurements

    Författare :Caroline Bergh; Conny Östman; Peter Haglund; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organophosphate esters; phthalate esters; air; dust; sampling; method development; GC MS; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Organophosphate and phthalate esters are polymer additives that are frequently found in air and dust in indoor environments. This thesis describes the development and application of air sampling and selective mass spectrometric (MS) determination of these two compound groups. LÄS MER

  2. 2. Analytical Quality by Design Method Development for Vaccine Characterization

    Författare :Lars Geurink; Catharina Sänger van de Griend; Mikael Hedeland; Martijn Schenning; Iulia Oita; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; viral vaccines; adenovirus; influenza; polio; COVID; corona; capillary electrophoresis; analytical quality by design; analytical method development; CGE; icIEF; CZE; crude cell suspension analysis; in-process sample analysis; quality control testing; biopharmaceutical characterization; Analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Sammanfattning : Vaccines that are safe, efficacious, and can be rapidly developed are needed to prevent and to react to emerging global infectious disease threats such as influenza, Polio, and Coronavirus diseases. Fast and reliable analytical methods are required without delay to support vaccine process and product development, characterization, and quality control testing. LÄS MER

  3. 3. Automation, hyphenation and multidimensional chromatography for PAH analysis : Analytical techniques to simplify sample complexity

    Författare :Hwanmi Lim; Roger Westerholm; Christoffer Bergvall; Stephen Wise; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polycyclic aromatic hydrocarbon; PAH; benzo[a]pyrene; B[a]P; carcinogenicity; cancer risk assessment; complex matrix; automation; hyphenation; multidimensional chromatography; two-dimensional; method translation; online fractionation; benz[j]aceanthrylene; B[j]A; relative potency factor; Analytical Chemistry; analytisk kemi;

    Sammanfattning : One group of organic environmental pollutants which are potentially hazardous to human health is polycyclic aromatic hydrocarbons (PAHs). These compounds consist of two or more benzene rings in their structure among which benzo[a]pyrene (B[a]P) is classified as a human carcinogen. LÄS MER

  4. 4. Characterization of dissolved organic matter : An analytical challenge

    Författare :Claudia Patriarca; Jonas Bergquist; Lars Tranvik; Jeffrey A. Hawkes; Jonathan Martin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

    Sammanfattning : Dissolved organic matter (DOM) is the prevalent form of organic carbon in most aquatic environments. It is an ultra-complex mixture that plays a crucial role in global carbon cycling. Despite its importance it is still poorly understood due to its extreme heterogeneity and intricacy. LÄS MER

  5. 5. Advances in analytical methodologies for studies of the platinum metallome in malignant cells exposed to cisplatin

    Författare :Yvonne Nygren; Erik Björn; Knut Irgum; Bente Gammelgaard; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Method development; Metallome; Inductively coupled plasma mass spectrometry; Electrospray ionization mass spectrometry; Liquid chromatography; Hyphenation; Organic modifier; Cisplatin; Platinum; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : The scientific progress about the important chemotherapeutic drug substance cisplatin (CDDP) and its function has often been rendered by data difficult to interpret, and still many questions about its mode of action remains to be clarified by the scientific community. However, studies of CDDP possess a high complexity due to; i) low intracellular concentration, ii) many potential biomolecule targets, iii) poor or unknown stability of the intact drug and its biomolecule adducts and iv) complex and varying sample matrices. LÄS MER