Sökning: "allopurinol"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet allopurinol.

  1. 1. Effect of Ischaemia-Reperfusion on Rabbit Kidney and Human Brain

    Författare :Jagdish Shivlal Gondalia; Göteborgs universitet; []
    Nyckelord :Free radicals; ischaemia-reperfusion; cell bioenergetics; NMR; ESR; carotid artery stenosis; endarterectomy; allopurinol; acetylcysteine; MMP-1; ICAM-1; MCP-9; oxLDL;

    Sammanfattning : Free radicals are produced in various organs at ischaemia-reperfusion. The final stage in radical damage is lipid peroxidation. We have demonstrated previously that a lipid-soluble antioxidant improves restoration of bioenergetics in rabbit kidneys after ischaemia, as reflected in 31P spectrometry. LÄS MER

  3. 2. The use of allopurinol and biodynamic modeling in the quantitative assessment of purine metabolism in man

    Författare :Geert van Waeg; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Endothelial dysfunction in the pulmanory circulation after cardiopulmonary bybass : with special reference to the reactivity to acetylcholine

    Författare :Monika Angdin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acetylcholine; acetylcysteine; allopurinol; antioxidants; cardiopulmonary bypass; heart surgery; L-arginine; nitric oxide; pulmonary circulation; reperfusion injury; vascular resistance; vitamin C; vitamin E.;

    Sammanfattning : The endothelium is important as a physical barrier between the bloodstream and the body tissues. It also plays an important role in the control of vasomotor tone, coagulation, and for the interaction between the vessel wall, leukocytes and platelets. One of the most important regulators released from the endothelium is nitric oxide (NO). LÄS MER

  5. 4. Trypsinogen and Its Activation in Acute Pancreatitis

    Författare :Ulf Petersson; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TAP; ERCP; carboxypeptidase B activation peptide; trypsinogen activation peptide; trypsinogen activation; Acute pancreatitis; trypsinogen; CAPAP; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Pancreatic enzymes, neutrophils, free radicals and cytokines are involved in the pathophysiology of AP. Clarification of their interaction and time-course will improve our understanding of AP and provide a better basis for treatment. LÄS MER

  7. 5. Discovery of N-hydroxyguanidines as novel electron acceptors of xanthine oxidase : Potential new drugs for treatment of ischemia and reperfusion injury

    Författare :Maija Dambrova; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; xanthine oxidase; N-hydroxyguanidine derivatives; ischemia and reperfusion; reduction; inhibition; superoxide; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Sammanfattning : Xanthine oxidase (EC 1.1.3.22) is one of the major enzymatic sources of oxygen-derived free radicals. LÄS MER