Sökning: "allergy and immunology"
Visar resultat 1 - 5 av 58 avhandlingar innehållade orden allergy and immunology.
1. Epigenetic changes and immunological features of chronic obstructive pulmonary disease
Sammanfattning : Background: Chronic obstructive pulmonary disease (COPD) is a heterogenous and chronic inflammatory syndrome with the lungs as its main target organ. Clinically, COPD is characterized by airflow limitation, chronic respiratory symptoms, and many extrapulmonary comorbidities. LÄS MER
2. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy
Sammanfattning : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. LÄS MER
3. Cytokine studies in the generation and treatment of IgE-mediated allergy
Sammanfattning : So called Th2 cytokines, such as IL-4 and IL-13 are responsible for the formation of IgE antibodies, the effector antibody in atopic allergy. Cytokines of Th1 type, for example IFN-g, inhibit these responses. This thesis describes work aimed at elucidating the cytokine production underlying IgE-mediated allergy. LÄS MER
4. On dysregulated inflammation and airway host defense
Sammanfattning : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. LÄS MER
5. Mast cells and their progenitors in respiratory diseases : Understanding their connection to lung function and airway inflammation
Sammanfattning : Mast cells are rare immune cells involved in allergic diseases, including asthma. These cells are derived from mast cell progenitors (MCps) that migrate to the peripheral tissues via the blood in response to allergic or non-allergic stimuli. LÄS MER