Sökning: "T cell suppression"
Visar resultat 1 - 5 av 140 avhandlingar innehållade orden T cell suppression.
1. Role of Inducible Nitric Oxide Synthase and Melatonin in Regulation of β-cell Sensitivity to Cytokines
Sammanfattning : The mechanisms of β-cell destruction leading to type 1 diabetes are complex and not yet fully understood, but infiltration of the islets of Langerhans by autoreactive immune cells is believed to be important. Activated macrophages and T-cells may then secrete cytokines and free radicals, which could selectively damage the β-cells. LÄS MER
2. A Study of Eosinophils – From the Human Thymus to Eosinophilic Esophagitis
Sammanfattning : Eosinophils are cells of the innate immune system. They primarily reside within tissues and are most numerous in the gastrointestinal tract but are absent from the healthy esophagus. During the inflammatory disease eosinophilic esophagitis, eosinophils infiltrate the esophagus but their function is unknown. LÄS MER
3. Recognition requirements and regulatory events directing T cell responses
Sammanfattning : The present study has considered cellular and molecular requirements in T cell responses. The central role of T cell growth factors (TCGF) in T cell responses prompted us to study the regulatory events directing TCGF production in lectin stimulated cultures. LÄS MER
4. T cell Tolerance - Cellular and molecular features of immune regulation
Sammanfattning : The immune system has evolved regulatory mechanisms in order to balance the effects of deleterious immune responses. Such immunological tolerance may be specifically acquired by lymphocytes, although different cells of the immune system participate in the induction and maintenance of tolerance. LÄS MER
5. B cell repertoire development in normal physiology and autoimmune disease
Sammanfattning : The B cell repertoire in the neonatal immune system (IS) is characterised by reactivity towards self-components, including other immunoglobulin (Ig) V-regions. These properties have been suggested to be a requirement for the development of a normal immune system. LÄS MER