Sökning: "Radiopharmaceutical therapy"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden Radiopharmaceutical therapy.

1. 1. Tools for the Advancement of Radiopharmaceutical Therapy

   Författare :Emma Mellhammar; Forskningsgruppen för Systemisk strålterapi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiopharmaceutical therapy; Nuclear medicine; Monte Carlo simulation; Intratherapeutic preclinical PET; Alpha particles; Beta Particles; radionuclides; Radiobiology; γ-H2AX; Dosimetry;

   Sammanfattning : Radiopharmaceutical therapy is used to treat cancers and other diseases with radiolabeled pharmaceuticals. The treatment targets specific cells, and the emitted ionizing radiation cause cytotoxic damage. Dosimetry is performed to estimate the absorbed dose from the energy deposited in the body. LÄS MER

3. 2. Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

   Författare :Helene Jönsson; Malmö Institutionen för kliniska vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Radiofarmaceutisk teknik; Radiopharmaceutical technology; absorbed dose. optimise; hyperthyroidism; therapy; 131-I; radioiodine; Nukleärmedicin; radiobiology; Nuclear medicine;

   Sammanfattning : Radioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. LÄS MER

4. 3. The Importance of Dosimetry and Radiobiology in Nuclear Medicine : Quantitative methods and modelling

   Författare :Anna Stenvall; Lund Medicinsk strålningsfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nuclear medicine; radionuclide therapy; radiopharmaceutical therapy; dosimetry; Monte Carlo modelling; radiobiology; ; γH2AX; DOTA-TATE; PET; SPECT;

   Sammanfattning : Nuclear medicine uses radioactive pharmaceuticals for diagnostic or therapeutic purposes. The ionizing radiation emitted from the radiopharmaceutical is partially absorbed within the patient's body and internal dosimetry is the method to estimate the absorbed dose to a tumour or risk organ. LÄS MER

5. 4. Internal dosimetry. Macroscopic, small-scale and microscopic perspectives

   Författare :Cecilia Hindorf; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiobiologi; Nukleärmedicin; radiobiology; Nuclear medicine; B-cell lymphoma; Radioimmunotherapy; Radionuclide therapy; Internal dosimetry; Radiopharmaceutical technology; Radiofarmaceutisk teknik;

   Sammanfattning : Internal dosimetry deals with the assessment of absorbed dose for radionuclides distributed inside the body. The absorbed dose is in its turn used for correlation with the biological effect caused by the irradiation. LÄS MER

7. 5. Methods for image-based dosimetry and radiobiological modelling in radionuclide therapy

   Författare :Johan Gustafsson; Lund Medicinsk strålningsfysik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radionuclide therapy; dosimetry; biologically effective dose; 177Lu-DOTATATE;

   Sammanfattning : In radionuclide therapy (RNT), radioactive pharmaceuticals are administered for therapeutic purposes. Dosimetry, i.e. the estimation of the absorbed dose to various targets, can potentially lead to a better understanding of the therapeutic effects in RNT and allow for individualization of the therapy. LÄS MER