Sökning: "Magnetic biosensor"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden Magnetic biosensor.

  1. 1. Differential Magnetic Biosensor using HTS SQUID Gradiometer

    Författare :Sobhan Sepehri; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high-Tc SQUID; magnetic bioassay; diagnostics; RCA; microfluidics; magnetic nanoparticle; point-of-care; rolling circle amplification; differential ac susceptibility; biosensor;

    Sammanfattning : A fundamental tool for containing an epidemic outbreak and mitigating its effects is early diagnostics. Currently, most of the diagnostic tests are performed by trained staff in centralized labs, which are expensive and time-consuming to establish and operate. Lack of access to such facilities could have devastating effects. LÄS MER

  3. 2. Brownian Relaxation Measurements of Magnetic Nanoparticles: Towards the Development of a Novel Biosensor System

    Författare :Andrea Prieto Astalan; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PSA; Magnetic susceptibility; Brownian relaxation; Biosensor; Prostate specific antigen; Magnetic nanoparticles; Frequency domain; Induction coils; Time domain;

    Sammanfattning : Magnetic measurements of the Brownian relaxation time of thermally blocked magnetic nanoparticles dispersed in a solution have been performed in order to determine the hydrodynamic size distribution of the particles. By measuring changes in the hydrodynamic size of the particles, the ammount of analytes attached to the surface of particles can be determined. LÄS MER

  4. 3. Molecular Diagnostics Using Volume-Amplified Magnetic Nanobeads : Towards the Development of a Novel Biosensor System

    Författare :Mattias Strömberg; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic Biosensors; Ferrofluid; Biofunctionalisation; Ferrofluidic Aging; Interbead Interactions; Magnetic Nanobeads; Complex Magnetisation; Brownian Relaxation; Padlock Probes; Rolling Circle Amplification; Engineering physics; Teknisk fysik;

    Sammanfattning : Micro- or nanometer sized magnetic particles (beads) currently have a vast range of life science applications in, for example, bioseparation techniques, cancer therapy, development of contrast agents and biosensing techniques. In the latter field, magnetic beads offer several unique advantages, including minimal background signals, physical and chemical stability and low manufacturing costs. LÄS MER

  5. 4. Detection of Biomolecules Using Volume-Amplified Magnetic Nanobeads

    Författare :Teresa Zardán Gómez de la Torre; Maria Strømme; Peter Svedlindh; Mikkel Fougt Hansen; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Magnetic biosensor; magnetic nanobeads; Brownian relaxation; padlock probe; rolling circle amplification; DNA detection; protein detection; Engineering Science with specialization in Nanotechnology and Functional Materials; Teknisk fysik med inriktning mot nanoteknologi och funktionella material;

    Sammanfattning : This thesis describes a new approach to biomolecular analysis, called the volume-amplified magnetic nanobead detection assay (VAM-DNA). It is a sensitive, specific magnetic bioassay that offers a potential platform for the development of low-cost, easy-to-use diagnostic devices. LÄS MER

  7. 5. Biomolecular Recognition Based on Field Induced Magnetic Bead Dynamics

    Författare :Rebecca Stjernberg Bejhed; Peter Svedlindh; Klas Gunnarsson; Maria Strömme; Teresa Zardán Gómez de la Torre; Christer Johansson; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Magnetic biosensor; magnetic nanoparticle; DNA detection; Teknisk fysik; Engineering Science;

    Sammanfattning : In this thesis, three different read-out techniques for biomolecular recognition have been studied. All three techniques rely on the change in dynamic behaviour of probe functionalised magnetic beads after binding to a biomolecular target complementary to the probe. LÄS MER