Sökning: "Klinisk virologi"

Visar resultat 21 - 25 av 71 avhandlingar innehållade orden Klinisk virologi.

  1. 21. Detection and Quantification of Variable Viral RNA by Real-Time PCR Assays

    Författare :Shaman Muradrasoli; Jonas Blomberg; Göran Friman; Maria Brytting; Uppsala universitet; []
    Nyckelord :Virology; Diagnosis of Viral RNA; QPCR; RNA virus; broadly targeted PCR; probe design strategy; Infectious diseases; Medicin; Medicine;

    Sammanfattning : As the area of nucleic acid based technologies develops, so will our understanding of how structural variations in DNA and RNA pathogens are associated with disease. The overall goal of this thesis is the development of broadly targeted measurement techniques for variable viral RNA by Real-Time PCR (here referred to as quantitative reverse transcriptase PCR, QRT-PCR). LÄS MER

  2. 22. Distribution and Effects of NO and CO in the Human Upper Respiratory Tract

    Författare :Jens Andersson; Helsingborg Kliniska Vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; transplantation; Microbiology; bacteriology; virology; serologi; Immunologi; serology; Otorhinolaryngology; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; Immunology; sinus; upper respiratory tract infection; nose; nitric oxide; neutrophil migration; middle ear; hemin; flow cytometry; allergy; carbon monoxide;

    Sammanfattning : Mucosal inflammation and airway hyperreactivity are regulated by hundreds of different mediators. The recent discovery of gaseous mediators, produced and active within the airways, opens new possibilities for identification of therapeutic targets and ways to monitor airway inflammation. LÄS MER

  3. 23. Tissue tropism among group A streptococci - importance of bacteria associated proteolytic activity

    Författare :Mikael Dag Svensson; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cysteine protease; plasminogen; M protein; Streptococcus pyogenes; tissue tropism; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Group A streptococcus (GAS) is one of the most common of bacterial pathogens infecting humans, frequently causing throat and skin infection. Some GAS strains have surface-expressed virulence factors called M proteins that bind human plasminogen with high affinity. LÄS MER

  4. 24. Cellular receptors for species B adenoviruses

    Författare :Marko Marttila; Niklas Arnberg; Göran Wadell; Tomas Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; CD80; CD86; Species B; Receptor; Internalization; Infection; Tropism; Virology; Virologi;

    Sammanfattning : Adenoviruses belong to the most common human pathogens. The severity of infection varies greatly, from subclinical to lethal, depending on the virus type and immune status of the infected host. The 51 known human adenovirus serotypes are divided into six species (A-F) based on characteristics such as tropism. LÄS MER

  5. 25. Human papillomavirus tropism : determinants of viral tissue specificity

    Författare :Nitesh Mistry; Magnus Evander; Ola Forslund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; papillomavirus; receptor; heparan sulfate; pI; lactoferrin; lactoferricin; transcription; long control region; tropism; Virology; Virologi;

    Sammanfattning : Cervical cancer is the second most common cancer among women worldwide and human papillomavirus (HPV) is a prerequisit for the development of this cancer. HPV belongs to the Papillomaviridae family and infects the basal layer of epithelial cells where it generally progresses into warts or condylomas. LÄS MER