Sökning: "Göran Wadell"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Göran Wadell.

  1. 1. Enteric adenovirus type 41 : genome organization and specific detection procedures

    Författare :Annika Allard; Göran Wadell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; EAd Ad41 EIA E1B detection PCR;

    Sammanfattning : Enteric adenoviruses (EAd) types 40 and 41 (Ad40 and Ad41) representing subgenus F, are primary pathogens of children being second only to rotaviruses as the most important cause of infantile diarrhea.The EAds differ from all other adenoviruses in their inability to grow in most conventional established cell lines and have been suggested to be deficient in some early gene functions since they could be complemented by Ad 5 early regions EIA and E1B. LÄS MER

  2. 2. Human adenoviruses : new bioassays for antiviral screening and CD46 interaction

    Författare :Emma Andersson; Göran Wadell; Sigvard Olofsson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; hemagglutination; antiviral; small molecule; screening; Virology; Virologi;

    Sammanfattning : Adenoviruses are common pathogens all over the world. The majority of the population has at some point been infected with an adenovirus. Although severe disease can occur in otherwise healthy individuals an adenovirus infection is most commonly self limited in these cases. LÄS MER

  3. 3. Cellular receptors for species B adenoviruses

    Författare :Marko Marttila; Niklas Arnberg; Göran Wadell; Tomas Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adenovirus; CD46; CD80; CD86; Species B; Receptor; Internalization; Infection; Tropism; Virology; Virologi;

    Sammanfattning : Adenoviruses belong to the most common human pathogens. The severity of infection varies greatly, from subclinical to lethal, depending on the virus type and immune status of the infected host. The 51 known human adenovirus serotypes are divided into six species (A-F) based on characteristics such as tropism. LÄS MER

  4. 4. Adenovirus species B: receptors, tropism and hematopoietic cells

    Författare :Anna Segerman; Göran Wadell; Ya-Fang Mei; Urs Greber; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Adenovirus; Species B; hematopoietic; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar; medicinsk virologi; Medical Virology;

    Sammanfattning : At present, the human adenoviruses (Ads) comprise 51 members, which have been classified into six species (A to F). In general, adenovirus (Ad) tissue tropism or disease patterns vary according to species, although adenoviruses from different species can sometimes cause the same symptoms. LÄS MER

  5. 5. The quest for new improved adenovirus gene therapy vectors against glioma tumours

    Författare :Johan Skog; Göran Wadell; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene therapy; virology; adenovirus; glioma; glioblastoma; Genterapi; virologi; adenovirus; gliom; glioblastom; Virology; Virologi;

    Sammanfattning : Gene therapy has received much attention the last decade as a method to correct a number of disorders arising from a defective gene. Gene therapy can be defined as the introduction of a functional genetic element into a cell for a therapeutic purpose. LÄS MER