Sökning: "Human Leukocyte Antigen HLA"
Visar resultat 1 - 5 av 59 avhandlingar innehållade orden Human Leukocyte Antigen HLA.
1. Human leukocyte antigen in sickness and in health : Ankylosing spondylitis and HLA in Sweden
Sammanfattning : The human leukocyte antigen (HLA) plays a major role in keeping us healthy, but some of the HLA alleles can contribute to disease susceptibility. One example is HLA-B*27, which confers increased susceptibility of ankylosing spondylitis and represents one of the strongest genetic associations found in any common human disease. LÄS MER
2. Dynamics of Human Leukocyte Antigen-D Related expression in bacteremic sepsis
Sammanfattning : Monocytic human leukocyte antigen-D related (mHLA-DR) expression determined by flow cytometry has been suggested as a biomarker of sepsisinduced immunosuppression.In order to facilitate use of HLA-DR in clinical practice, a quantitative real-time PCR technique measuring HLA-DR at the transcription level was developed and evalutated. LÄS MER
3. Immunological risk factors in heart transplantation
Sammanfattning : .... LÄS MER
4. Tapasin - The star of the show in HLA-I maturation
Sammanfattning : Human leukocyte antigen class I (HLA-I) molecules are present on the cell surface of all nucleated cells. They bind intracellular peptides and present them to the immune system thus providing a readout to cytotoxic T-cells about the status of a cell. LÄS MER
5. Immunogenetics of Childhood Type 1 Diabetes in Immigrant Patients in Sweden. Migration Studies on Type 1 Diabetes
Sammanfattning : This thesis examined whether the offspring of immigrants (non-Swedes) to Sweden are at increased risk of Type 1 Diabetes (T1D) when they are born or live in Sweden. It also evaluated if their T1D and T2D-related genes differed from Swedish patients and whether this genetic heritage determined the types and existence of islet autoantibodies at time of diagnosis and affected the classification of diabetes. LÄS MER