Sökning: "Histone H3"

Visar resultat 1 - 5 av 51 avhandlingar innehållade orden Histone H3.

  1. 1. Methyltransferase Ash1, histone methylation and their impact on Polycomb repression

    Författare :Eshagh Dorafshan Esfahani; Yuri B. Schwartz; Jan Larsson; Dale Dorsett; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Trithorax Group proteins; Polycomb Group proteins; PRC1; PRC2; PRE; histone methylation; histone ubiquitylation; Ash1; SET domain; H3K36; H3K27; Drosophila;

    Sammanfattning : Antagonistic interactions between Polycomb Group (PcG) and Trithorax Group (TrxG) proteins orchestrate the expression of key developmental genes. Distinct maternally loaded repressors establish the silenced state of these genes in cells where they should not be expressed and later PcG proteins sense whether a target gene is inactive and maintain the repression throughout multiple cell divisions. LÄS MER

  3. 2. Chromatin, histones, and epigenetic tags

    Författare :Elisavet Koutzamani; Ingemar Rundquist; Herbert Lindner; Sergey Belikov; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chromatin; histones; histone variants; epigenetics; histone H4 methylation; linker histone phosphorylation; Medical cell biology; Medicinsk cellbiologi;

    Sammanfattning : The fundamental building blocks of chromatin are the nucleosomes. Each such unit is composed of about 200 bp of DNA, the well-conserved core histones (H2A, H2B, H3 and H4) and a linker histone (H1). LÄS MER

  4. 3. Phylogeny and Taxonomy of Childia (Acoela) : New characters for unraveling acoel phylogenies from molecules, ultrastructure, immunocytochemistry and confocal microscopy

    Författare :Yonas Isaak Tekle; Ulf Jondelius; Mikael Thollesson; Isabel Sanmartin; Kennet Lundin; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Childiidae; Childia; Paraphanostoma; Acoela; phylogeny; taxonomy; morphology; 18S rRNA; 28S rRNA; Histone H3; ultrastructure; confocal; phalloidin; immunocytochemistry; Biologi; Biology; Biologi;

    Sammanfattning : This thesis presents a comprehensive phylogenetic and taxonomic study of an acoel subgroup, the Childiidae. Members of this taxon are characterized by well-developed male copulatory organs with conical/cylindrical stylets. LÄS MER

  5. 4. Biomarkers in endotoxemia with a special interest in citrullinated histone H3

    Författare :Sofie Paues Göranson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Sepsis with multi-organ failure has an unacceptably high mortality rate of 25- 30% despite the use of antibiotics and modern intensive care. Attenuating the multi-organ failure and finding new biomarkers for early detection of septic shock would be of high clinical relevance in order to improve outcome. LÄS MER

  7. 5. The Interaction of the Adenovirus E1B-55K Protein with a Histone Deacetylase Complex: Its Importance in Regulation of P53 Protein Functions

    Författare :Tanel Punga; Göran Akusjärvi; Klas G. Wiman; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; E1B-55K; p53; histone acetylation; Sin3; Biokemi; Biochemistry; Biokemi;

    Sammanfattning : The human tumour suppressor protein p53 is an effective inhibitor of cell growth, by inducing cell cycle arrest and apoptosis. However, p53-induced cell growth inhibition can be detrimental for virus multiplication. Therefore, viruses encode for proteins, which can interfere with the functions of the p53 protein. LÄS MER