Sökning: "mitochondrial gene expression"

Visar resultat 1 - 5 av 156 avhandlingar innehållade orden mitochondrial gene expression.

1. 1. Organization and regulation of mitochondrial gene expression

   Författare :Roger Salvatori; Martin Ott; Benoit Kornmann; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; mitochondrial gene expression; post-transcriptional regulation; mitochondrial ribosome; protein-protein proximity; BioID; feedback loop; Biochemistry; biokemi;

   Sammanfattning : Mitochondria possess their own genome, remnant of the ancestral eubacterial endosymbiont DNA. This mitochondrial genome encodes mostly few key subunits of the respiratory chain. In order to synthesize these few proteins, mitochondria contain a complete gene expression machinery. LÄS MER

3. 2. Organization of mitochondrial gene expression in yeast : Specific features of organellar protein synthesis

   Författare :Kirsten Kehrein; Martin Ott; Thomas A Fox; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mitochondria; translation; bc1 complex; ribosome; gene expression; Biochemistry; biokemi;

   Sammanfattning : Mitochondria contain their own genetic system, encoding key subunits of the oxidative phosphorylation system. These subunits are expressed by an organelle-specific gene expression machinery. LÄS MER

4. 3. The mitoribosome as a hub for integrating mitochondrial gene expression : Regulation of translation and early assembly of cytochrome b

   Författare :Andreas Carlström; Martin Ott; Chris Meisinger; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; mitochondrial ribosome; translation regulation; feedback loop; biokemi; Biochemistry;

   Sammanfattning : The mitochondrial proteome is a mosaic of proteins from two different genetic systems. The majority of mitochondrial proteins are encoded in the nuclear genome and are synthesized in the cytosol before imported to mitochondria. LÄS MER

5. 4. Novel methods to study mitochondrial gene expression and homeostasis

   Författare :Magdalena Rzepka; Martin Ott; Christof Osman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondria; gene expression; metabolism; biokemi; Biochemistry;

   Sammanfattning : Mitochondria are semi-autonomous organelles that harbor one of the main cellular processes – energy conversion. Nutrients available in the environment are taken up by cells and transformed into metabolites that can be used for synthesis of ATP, the energy currency of the cell. LÄS MER

7. 5. Mitochondrial translation and its impact on protein homeostasis and aging

   Författare :Tamara Suhm; Martin Ott; Aleksandra Trifunovic; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mitochondrial ribosome; mitochondrial translation accuracy; mitochondrial communication; interorganellar communication; stress signaling; proteostasis; aging; yeast genetics; mitochondrial protein quality control; mitochondrial membrane protein insertion; Biochemistry; biokemi;

   Sammanfattning : Besides their famous role as powerhouse of the cell, mitochondria are also involved in many signaling processes and metabolism. Therefore, it is unsurprising that mitochondria are no isolated organelles but are in constant crosstalk with other parts of the cell. LÄS MER