Sökning: "Klas G. Wiman"

Hittade 1 avhandling innehållade orden Klas G. Wiman.

1. 1. The Interaction of the Adenovirus E1B-55K Protein with a Histone Deacetylase Complex: Its Importance in Regulation of P53 Protein Functions

   Författare :Tanel Punga; Göran Akusjärvi; Klas G. Wiman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; adenovirus; E1B-55K; p53; histone acetylation; Sin3; Biokemi; Biochemistry; Biokemi;

   Sammanfattning : The human tumour suppressor protein p53 is an effective inhibitor of cell growth, by inducing cell cycle arrest and apoptosis. However, p53-induced cell growth inhibition can be detrimental for virus multiplication. Therefore, viruses encode for proteins, which can interfere with the functions of the p53 protein. LÄS MER