Sökning: "Herpes simplex virus"

Visar resultat 6 - 10 av 75 avhandlingar innehållade orden Herpes simplex virus.

  1. 6. Activation of Herpes simplex virus type 1 origin of DNA replication

    Författare :Alireza Aslani; Göteborgs universitet; []
    Nyckelord :DNA replication; Herpes simplex virus; helicase; UL9; OBP; ICP8; ATP; oriS; hairpin;

    Sammanfattning : Herpes simplex virus type 1 has been used to study the molecular mechanism of DNA replication. Initiation of DNA replication takes place at specific regions called origins of replication. The HSV-1 genome contains three origins of replication, one copy of oriL and two copies of oriS. LÄS MER

  3. 7. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products

    Författare :Mårten Strand; Göran Wadell; Mikael Elofsson; Ya-Fang Mei; Lieve Naesens; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; virology; antiviral; adenovirus; herpes simplex virus; small molecule; inhibitor; hsv; drug discovery; medicinsk virologi; Medical Virology; datorlingvistik; computational linguistics; mikrobiologi; Microbiology;

    Sammanfattning : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. LÄS MER

  4. 8. Herpes simplex virus infection: epidemiological aspects and analysis of the type-specific antibody response

    Författare :Petra Tunbäck; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpes simplex virus; first episode genital herpes; seroepidemiology type-specific antibody-response; glycoprotein G-1; epitope-mapping;

    Sammanfattning : Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) are ubiquitous viruses, often leading to asymptomatic infections in humans. However, different clinical presentations can be seen including recurrent oral or genital lesions, meningitis and neonatal herpes. LÄS MER

  5. 9. Genetic variants of herpes simplex virus type 1

    Författare :Elham Rekabdar; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; s simplex virus type 1; glycoprotein G; genovariants; intrastrain diversity;

    Sammanfattning : Herpes simplex virus type 1 (HSV-1) virus causes oral as well as genital lesions, and, on rare occasions, focal encephalitis and severe neonatal infections. Due to the partly overlapping clinical manifestations of infection with HSV-1 and its closest relative among herpesviruses, HSV-2, diagnostic methods are required to discriminate between infections with these two viruses. LÄS MER

  7. 10. Anti-herpes simplex virus activities of sulfomannan oligosaccharide PI-88 and disulfated cyclitols

    Författare :Maria Ekblad; Göteborgs universitet; []
    Nyckelord :herpes simplex virus; antiviral drugs; viral glycoproteins; heparan sulfate mimetic; PI-88;

    Sammanfattning : Herpes simplex virus (HSV) initiates invasion of human cells by binding to the cell surface heparan sulfate (HS) glycosaminoglycan chains. This step is mediated by the viral envelope glycoproteins gC and/or gB. LÄS MER