Sökning: "Genes"

Visar resultat 21 - 25 av 4465 avhandlingar innehållade ordet Genes.

  1. 21. Genetic Mapping of Susceptibility Genes for Systemic Lupus Erythematosus

    Författare :Bo Johanneson; Jean Pierre Hugot; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular genetics; Association analysis; Candidate gene; Complex disease; Genome scan; Linkage analysis; Mapping; Susceptibility genes; Systemic lupus erythematosus; Genetik; Genetics; Genetik; medicinsk genetik; Medical Genetics;

    Sammanfattning : Systemic lupus erythematosus (SLE) is a complex autoimmune disease with unknown etiology. The aim of this thesis was to identify susceptibility regions through genetic mapping, using model-based linkage analysis on nuclear and extended SLE multicase families. LÄS MER

  3. 22. Amelioration of Horizontally Transferred Genes

    Författare :Torbjörn Karfunkel; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; transposoner; horisontell genöverföring; dna; bakterier; plasmider;

    Sammanfattning : The importance of Horizontal (Lateral) Gene Transfer has attracted much attention during the last few decades. It is a very important factor in bacterial evolution and ecology, and it has great implications on human life as well. LÄS MER

  4. 23. The Gene Repertoire of G protein-coupled Receptors : New Genes, Phylogeny, and Evolution

    Författare :Þóra Kristín Bjarnadóttir; Helgi B. Schiöth; Robert Fredriksson; Kurt Kristiansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Bioinformatics; Evolution; GPCR; Phylogeny; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCRs) is one of the largest protein families of mammalian genomes and can be divided into five main families; Glutamate, Rhodopsin, Adhesion, Frizzled, and Secretin. GPCRs participate in most major physiological functions, contributing to the fact that they are important targets in drug discovery. LÄS MER

  5. 24. Chromatin remodelling of ribosomal genes - be bewitched by B-WICH

    Författare :Anna Vintermist; Ann-Kristin Östlund Farrants; Ross D. Hannan; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chromatin remodelling; ribosomal genes; rDNA; transcription; RNA polymerase I transcription; RNA polymerase III transcription; Cell Biology; cellbiologi;

    Sammanfattning : Transcription of the ribosomal genes accounts for the majority of transcription in the cell due to the constant high demand for ribosomes. The number of proteins synthesized correlates with an effective ribosomal biogenesis, which is regulated by cell growth and proliferation. LÄS MER

  7. 25. Barley defense genes against aphids

    Författare :Aleksandra Losvik; Lisbeth Jonsson; Ulla Rasmussen; Robert Glinwood; Bogumił Leszczyński; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Aphid resistance; protease inhibitor; lipoxygenase; induced plant resistance; volatiles; Hordeum vulgare; Rhopalosiphum padi; Myzus persicae; Plant Physiology; växtfysiologi;

    Sammanfattning : Aphids are insect pests with major importance worldwide. By feeding from plant phloem, they directly withdraw nutrients. The feeding injury is often visible in the form of leaf rolling, chlorosis, necrosis or plant deformation. Their pest status is attributed also to vectoring of plant viruses. LÄS MER