Sökning: "Fibroblast"

Visar resultat 21 - 25 av 268 avhandlingar innehållade ordet Fibroblast.

  1. 21. Fibroblast growth factor-8 regulation of breast cancer cell growth

    Författare :Emeli Nilsson; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Expression of fibroblast growth factor-8 (FGF-8) is increased in a large number of breast cancers. In in vitro and in vivo breast cancer models FGF-8 promotes growth, invasion and angiogenesis. LÄS MER

  3. 22. The role of fibroblast growth factor 19 in human liver

    Författare :Heléne Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Bile acids are synthesized in the liver and are essential for intestinal absorption of lipids. Bile acid homeostasis is crucial and if not maintained, bile acids can accumulate to toxic levels and cause severe damage to the liver. LÄS MER

  4. 23. Aspects of Fibroblast Growth Factor 23 in Mild to Moderate Renal Dysfunction

    Författare :Per-Anton Westerberg; Torbjörn Linde; Östen Ljunggren; Björn Wikström; Marcus Ketteler; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; phosphate; mineral metabolism; elderly; mortality; Medicin; Medicine;

    Sammanfattning : Disturbances in mineral metabolism contribute to vascular calcification and mortality risk in chronic kidney disease (CKD). Serum levels of fibroblast growth factor (FGF)23, a bone derived, phosphaturic peptide, are associated with cardiovascular mortality in CKD. LÄS MER

  5. 24. Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

    Författare :Lars Lundin; Lena Claesson-Welsh; Marco Presta; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR; dimerisation; signal transduction; heparan sulfate; proteoglycan; heparin; VEGF; embryonal stem cell; endothelial cell; differentiation; Patologi; Pathology; Patologi;

    Sammanfattning : Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. LÄS MER

  7. 25. Functional Characterization of Tyrosine Transporters in fibroblast from Healthy Controls and Schizophrenic Patients

    Författare :Ravi Vumma; Nikolaos Venizelos; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblasts; Schizophrenia; Precursor of Dopamine; Biological Transport; Active cellphysiology; Tyrosine and alanine transport; System-L; LAT1; LAT2; LAT3; LAT4; MEDICINE; MEDICIN; Internal medicine; Invärtesmedicin; Neurology; Neurologi; Neurology; Neurologi;

    Sammanfattning : Cultured human fibroblasts offer an advantageous system to investigate the amino acid transport properties without confounding the affects of disease state and its treatment in many systemic psychiatric disorders. In previous studies, fibroblast cells have been used to investigate the tyrosine transport across plasma membranes in patients with schizophrenia and autism with out characterizing the particular amino acid transporters. LÄS MER