Sökning: "System-L"

Hittade 4 avhandlingar innehållade ordet System-L.

  1. 1. Functional Characterization of Tyrosine Transporters in fibroblast from Healthy Controls and Schizophrenic Patients

    Författare :Ravi Vumma; Nikolaos Venizelos; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fibroblasts; Schizophrenia; Precursor of Dopamine; Biological Transport; Active cellphysiology; Tyrosine and alanine transport; System-L; LAT1; LAT2; LAT3; LAT4; MEDICINE; MEDICIN; Internal medicine; Invärtesmedicin; Neurology; Neurologi; Neurology; Neurologi;

    Sammanfattning : Cultured human fibroblasts offer an advantageous system to investigate the amino acid transport properties without confounding the affects of disease state and its treatment in many systemic psychiatric disorders. In previous studies, fibroblast cells have been used to investigate the tyrosine transport across plasma membranes in patients with schizophrenia and autism with out characterizing the particular amino acid transporters. LÄS MER

  3. 2. The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta

    Författare :Sara Roos; Göteborgs universitet; []
    Nyckelord :amino acids; fetal growth restriction; human; mammalian target of rapamycin; membrane transporters; metabolism; placenta; pregnancy; system A; system L; taurine transporter;

    Sammanfattning : Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there is no specific treatment of this condition. LÄS MER

  4. 3. Placental transport of glucose and amino acids in early pregnancy. Cellular mechanisms, regulation and relation to diabetes

    Författare :Anette Ericsson; Göteborgs universitet; []
    Nyckelord :placental transport; diabetes; first trimester; GLUT; system A; hyperglycemia;

    Sammanfattning : Despite strict glycemic control of the pregnant woman with type 1 diabetes fetal overgrowth is still common. The first trimester is often characterized by sub-optimal glucose levels and elevated HbA1C in early pregnancy is a predictor of fetal overgrowth. LÄS MER

  5. 4. Dissection of immunity controlling spread and growth of Listeria monocytogenes in neuronal cells

    Författare :Yuxuan Jin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :L. monocytogenes; nervous system; neuroinvasion; IFN-ã; CSF-1; neuron; NK cells; T cells; MHC;

    Sammanfattning : Listeria monocytogenes is a Grain-positive, facultative intracellular bacterium that causes severe infections in the nervous system of domestic animals and humans. Rhombencephalitis (brainstem encephalitis) due to L. monocytogenes, is a localized brainstem infection that is frequent in ruminants, and has been reported in humans as well. LÄS MER