Sökning: "FCGBP"

Hittade 4 avhandlingar innehållade ordet FCGBP.

  1. 1. The Role of FCGBP in Mucus - Structure, Processing and Function

    Författare :Erik Ehrencrona; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Sammanfattning : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. LÄS MER

  2. 2. Mucus associated proteins and their functional role in the distal intestine

    Författare :Joakim H. Bergström; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intestine; mucus; bacteria; MUC2; AGR2; FCGBP; ZG16;

    Sammanfattning : The mammalian intestine, especially the large intestine, harbors complex societies of beneficial bacteria coexisting with the host. This is a mutualistic relationship, where the host provides nutrients and a favorable environment while the bacteria in return ferment indigestible polysaccharides to short chain fatty acids. LÄS MER

  3. 3. The MUC2 mucin -A network in the intestinal protective mucus

    Författare :Malin E V Johansson; Göteborgs universitet; []
    Nyckelord :mucus; Muc2; trimer; proteomics; intestine; colitis; DSS;

    Sammanfattning : The intestine is covered by mucus that is the first line of defence of the epithelium. The main structural component of the intestinal mucus is the MUC2 mucin. This is a large glycoprotein with two long and heavily O-glycosylated mucin domains. LÄS MER

  4. 4. Study of the colonic mucus layer by mass spectrometry

    Författare :Sjoerd van der Post; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MUC2; mucin; intestine; proteomics; mass spectrometry;

    Sammanfattning : The mucus covering our internal mucosal surfaces is a part of the innate immune system, and the first line of defense against microbial challenges. The need of an efficient defense system is especially important in the lower parts of the digestive tract where the microbiota reaches its highest density. LÄS MER